Cover article - Contribution of non-circadian neurons to the temporal organization of locomotor activity

Our cover article characterizes the impact of different putative postsynaptic partners of the small ventral lateral neurons on the control of rhythmic locomotor behavior. M. Fernanda Ceriani and team found that some of these novel neuronal clusters are relevant for the control of locomotor activity.

Featured article - Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases

Frank Kozielski and colleagues have developed a 96-well crystallization screen for viral RNA-dependent RNA polymerases (RdRps). Read about this platform for streamlining the crystallisation of RdRps and implementing structure-based drug discovery programs.

First person interviews

Have you seen our interviews with the early-career first authors of our papers? Recently, we caught up with first authors Sarah Hoffman, Amani Hassan, Eriko Seo, Yunlong Li and Klytaimnistra Kiouptsi.

Why should you publish your next paper in BiO?

Biology Open has strong credentials and publishing with us is easy and fast. BiO aims to provide rapid publication for scientifically sound observations and valid conclusions in developmental, cell, experimental and translational biology. Submit your paper here; you’ll be in good company.

Recent disease mechanism highlights in BiO – Timothy Plageman and team investigate folic acid’s modification of epithelial cell shape during morphogenesis, shedding light onto the mechanism by which folic acid may prevent neural tube defects.

Transfer to Biology Open

If your submission to one of our other journals, Development, Journal of Cell Science, Journal of Experimental Biology or Disease Models & Mechanisms, is unsuccessful, did you know you can transfer your paper and any reviews directly to Biology Open? The majority of papers transferred with reviews are accepted for publication. Find out how here.

PreLights - Short-range interactions govern cellular dynamics in microbial multi-genotype systems

Connor Rosen highlights two preprints which show that microbial conversations dictate growth by measuring and modeling the crosstalk between individual microbial cells.