Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Interviews
    • Sign up for alerts
  • About us
    • About BiO
    • Editors and Board
    • Editor biographies
    • Grants and funding
    • Workshops and Meetings
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • Biology Open transfer option
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact BiO
    • Advertising
    • Feedback
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

User menu

  • Log in

Search

  • Advanced search
Biology Open
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

supporting biologistsinspiring biology

Biology Open

Advanced search

RSS   Twitter   Facebook   YouTube

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Interviews
    • Sign up for alerts
  • About us
    • About BiO
    • Editors and Board
    • Editor biographies
    • Grants and funding
    • Workshops and Meetings
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • Biology Open transfer option
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact BiO
    • Advertising
    • Feedback
Research Article
Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells
Ahmed El-Badawy, Nehal I. Ghoneim, Mohamed A. Nasr, Hoda Elkhenany, Toka A. Ahmed, Sara M. Ahmed, Nagwa El-Badri
Biology Open 2018 7: bio034181 doi: 10.1242/bio.034181 Published 25 July 2018
Ahmed El-Badawy
Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, 6th of October City 12588, Egypt
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ahmed El-Badawy
Nehal I. Ghoneim
Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, 6th of October City 12588, Egypt
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mohamed A. Nasr
Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, 6th of October City 12588, Egypt
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hoda Elkhenany
Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, 6th of October City 12588, EgyptDepartment of Surgery, College of Veterinary Medicine, Alexandria University, Alexandria 22785, Egypt
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Toka A. Ahmed
Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, 6th of October City 12588, Egypt
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sara M. Ahmed
Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, 6th of October City 12588, Egypt
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nagwa El-Badri
Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, 6th of October City 12588, Egypt
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Nagwa El-Badri
  • For correspondence: nelbadri@zewailcity.edu.eg
  • Article
  • Figures & tables
  • Supp info
  • Info & metrics
  • eLetters
  • PDF + SI
  • PDF
Loading

Article Information

vol. 7 no. 7, bio034181

DOI 
https://doi.org/10.1242/bio.034181
PubMed 
29907642

Published By 
The Company of Biologists Ltd
Online ISSN 
2046-6390
History 
  • Received March 16, 2018
  • Accepted June 1, 2018
  • Published online July 25, 2018.
Posted online 
June 15, 2018
Copyright & Usage 
© 2018. Published by The Company of Biologists Ltd http://creativecommons.org/licenses/by/3.0This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Article Versions

  • Previous version (June 15, 2018 - 07:43).
  • You are viewing the most recent version of this article.

Author Information

  1. Ahmed El-Badawy1,
  2. Nehal I. Ghoneim1,
  3. Mohamed A. Nasr1,
  4. Hoda Elkhenany1,2,
  5. Toka A. Ahmed1,
  6. Sara M. Ahmed1 and
  7. Nagwa El-Badri1,*
  1. 1Center of Excellence for Stem Cells and Regenerative Medicine (CESC), Zewail City of Science and Technology, 6th of October City 12588, Egypt
  2. 2Department of Surgery, College of Veterinary Medicine, Alexandria University, Alexandria 22785, Egypt
  1. ↵*Author for correspondence (nelbadri{at}zewailcity.edu.eg)
View Abstract

Article usage

Usage statistics are calculated at the beginning of each month for the previous month.

Usage statistics: June 2018 to January 2019

AbstractFullPdf
Jun 20183920121
Jul 20181682693
Aug 201819516172
Sep 2018506053
Oct 2018465045
Nov 2018323856
Dec 2018253334
Total 2018908368474
Jan 2019233518
Total 2019233518
Total931403492

Statistics from Altmetric.com

Previous ArticleNext Article
Back to top
Previous ArticleNext Article

This Issue

RSSRSS

Keywords

  • HTERT
  • CSCs
  • Cancer metastasis
  • Chemoresistance

 Download PDF

Email

Thank you for your interest in spreading the word on Biology Open.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells
(Your Name) has sent you a message from Biology Open
(Your Name) thought you would like to see the Biology Open web site.
Share
Research Article
Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells
Ahmed El-Badawy, Nehal I. Ghoneim, Mohamed A. Nasr, Hoda Elkhenany, Toka A. Ahmed, Sara M. Ahmed, Nagwa El-Badri
Biology Open 2018 7: bio034181 doi: 10.1242/bio.034181 Published 25 July 2018
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Research Article
Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells
Ahmed El-Badawy, Nehal I. Ghoneim, Mohamed A. Nasr, Hoda Elkhenany, Toka A. Ahmed, Sara M. Ahmed, Nagwa El-Badri
Biology Open 2018 7: bio034181 doi: 10.1242/bio.034181 Published 25 July 2018

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Alerts

Please log in to add an alert for this article.

Sign in to email alerts with your email address

Article Navigation

  • Top
  • Article
    • ABSTRACT
    • INTRODUCTION
    • RESULTS
    • DISCUSSION
    • MATERIALS AND METHODS
    • Acknowledgements
    • Footnotes
    • References
  • Figures & tables
  • Supp info
  • Info & metrics
  • eLetters
  • PDF + SI
  • PDF

Related articles

Cited by...

More in this TOC section

  • Ultraviolet B-induced Otx2 expression in lens epithelial cells promotes epithelial–mesenchymal transition
  • Joint moments during sprinting in unilateral transfemoral amputees wearing running-specific prostheses
  • Gcn5 histone acetyltransferase is present in the mitoplasts
Show more RESEARCH ARTICLE

Similar articles

Other journals from The Company of Biologists

Development

Journal of Cell Science

Journal of Experimental Biology

Disease Models & Mechanisms

Advertisement

Cover article - Contribution of non-circadian neurons to the temporal organization of locomotor activity

A confocal projection of an expression pattern of a novel neuronal cluster that participates in the control of locomotor activity in Drosophila

Our cover article characterizes the impact of different putative postsynaptic partners of the small ventral lateral neurons on the control of rhythmic locomotor behavior. M. Fernanda Ceriani and team found that some of these novel neuronal clusters are relevant for the control of locomotor activity.


Featured article - Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases

Light micrographs of some of the crystals obtained with the RdRp screen

Frank Kozielski and colleagues have developed a 96-well crystallization screen for viral RNA-dependent RNA polymerases (RdRps). Read about this platform for streamlining the crystallisation of RdRps and implementing structure-based drug discovery programs.


First person interviews

First authors Sarah Hoffman, Amani Hassan, Eriko Seo, Yunlong Li and Klytaimnistra Kiouptsi

Have you seen our interviews with the early-career first authors of our papers? Recently, we caught up with first authors Sarah Hoffman, Amani Hassan, Eriko Seo, Yunlong Li and Klytaimnistra Kiouptsi.


Why should you publish your next paper in BiO?

Biology Open has strong credentials and publishing with us is easy and fast. BiO aims to provide rapid publication for scientifically sound observations and valid conclusions in developmental, cell, experimental and translational biology. Submit your paper here; you’ll be in good company.

Part of Fig. 4: Folic acid rescue is MLCK and Src-kinase dependent

Recent disease mechanism highlights in BiO – Timothy Plageman and team investigate folic acid’s modification of epithelial cell shape during morphogenesis, shedding light onto the mechanism by which folic acid may prevent neural tube defects.


Transfer to Biology Open

If your submission to one of our other journals, Development, Journal of Cell Science, Journal of Experimental Biology or Disease Models & Mechanisms, is unsuccessful, did you know you can transfer your paper and any reviews directly to Biology Open? The majority of papers transferred with reviews are accepted for publication. Find out how here.


PreLights - Short-range interactions govern cellular dynamics in microbial multi-genotype systems

Connor Rosen highlights two preprints which show that microbial conversations dictate growth by measuring and modeling the crosstalk between individual microbial cells.

Articles

  • Accepted manuscripts
  • Issue in progress
  • Latest complete issue
  • Issue archive
  • Archive by article type
  • Interviews
  • Sign up for alerts

About us

  • About BiO
  • Editors and Board
  • Editor biographies
  • Grants and funding
  • Workshops and Meetings
  • The Company of Biologists

For Authors

  • Submit a manuscript
  • Aims and scope
  • Presubmission enquiries
  • Article types
  • Manuscript preparation
  • Cover suggestions
  • Editorial process
  • Promoting your paper
  • Open Access
  • Biology Open transfer option

Journal Info

  • Journal policies
  • Rights and permissions
  • Media policies
  • Reviewer guide
  • Sign up for alerts

Contact

  • Contact BiO
  • Advertising
  • Feedback

Twitter   YouTube   LinkedIn

© 2019   The Company of Biologists Ltd   Registered Charity 277992