- Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin
Summary: ER stress triggers calpain-dependent Bif-1 activation and induction of autophagosome maturation by promoting ATG9/Bif-1 vesicle trafficking and fusion with LC3 bodies.
- Ole1, fatty acid desaturase, is required for Atg9 delivery and isolation membrane expansion during autophagy in Saccharomyces cerevisiae
Summary: Isolation membrane expansion in yeast autophagy requires mono-unsaturated fatty acids generated by Ole1, fatty acid desaturase during delivery of Atg9 to the PAS/autophagosome from its cellular reservoir.
- METACASPASE9 modulates autophagy to confine cell death to the target cells during Arabidopsis vascular xylem differentiation
Summary: In cell cultures that simulate Arabidopsis xylem differentiation, METACASPASE9 modulates the level of autophagy during programmed cell death to prevent ectopic death of the surrounding cells.
- Atg9 is required for intraluminal vesicles in amphisomes and autolysosomes
Summary: The disappearance of intraluminal vesicles in amphisomes/autolysosomes upon Atg9 depletion suggests that Atg9 has a specific role in intraluminal vesicle formation in autophagic compartments.