- Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation
Summary: Polo-like kinase phosphorylation determines proper centrosome scaffold size and density, but not function or maintenance, in Caenorhabditis elegans embryos.
- Caenorhabditis elegans glutamylating enzymes function redundantly in male mating
Summary: Although mutations in individual microtubule glutamylating enzymes do not disrupt essential microtubule functions in C. elegans, combining mutations in three enzymes uncovers a redundant function for glutamylation in male mating.
- C. elegans flavin-containing monooxygenase-4 is essential for osmoregulation in hypotonic stress
Summary: C. elegans lacking fmo-4 fail to clear body water following hypotonic exposure resulting in rapid swelling and rupture, indicating that FMO-4 is required in the hypoosmotic stress response.
- NGT-3D: a simple nematode cultivation system to study Caenorhabditis elegans biology in 3D
Summary: We have designed a three dimensional nematode habitat for use in the lab, called NGT-3D, where growth, fertility and lifespan are comparable with the traditional two dimensional lab environment.