Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Interviews
    • Sign up for alerts
  • About us
    • About BiO
    • Editors and Board
    • Editor biographies
    • Grants and funding
    • Workshops and Meetings
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • Biology Open transfer option
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact BiO
    • Advertising
    • Feedback
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

User menu

  • Log in

Search

  • Advanced search
Biology Open
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

supporting biologistsinspiring biology

Biology Open

Advanced search

RSS   Twitter   Facebook   YouTube

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Interviews
    • Sign up for alerts
  • About us
    • About BiO
    • Editors and Board
    • Editor biographies
    • Grants and funding
    • Workshops and Meetings
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
    • Biology Open transfer option
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact BiO
    • Advertising
    • Feedback

Development

  • RESEARCH ARTICLE
    Promoter-enhancer looping and shadow enhancers of the mouse αA-crystallin locus
    Rebecca S. McGreal-Estrada, Louise V. Wolf, Ales Cvekl
    Biology Open 2018 7: bio036897 doi: 10.1242/bio.036897 Published 7 December 2018

    Summary: The αA-crystallin ranks amongst the most highly expressed tissue-specific genes. It is an advantageous model system to probe both promoter-enhancer looping and to identify distal enhancers and their temporal/spatial activities.

  • RESEARCH ARTICLE
    Ubiquitin A-52 residue ribosomal protein fusion product 1 (Uba52) is essential for preimplantation embryo development
    Jiude Mao, Chad O'Gorman, Miriam Sutovsky, Michal Zigo, Kevin D. Wells, Peter Sutovsky
    Biology Open 2018 7: bio035717 doi: 10.1242/bio.035717 Published 2 October 2018

    Summary: Ubiquitin A-52 residue ribosomal protein fusion product 1 (Uba52), a ubiquitin-ribosomal fusion gene, is a major source of ubiquitin protein for covalent modification of proteinaceous substrates recycled by ubiquitin-proteasome system. Using CRISPR/cas9 gene editing tool, we demonstrate that that Uba52 gene is essential in early embryogenesis in mammals.

  • METHODS & TECHNIQUES
    High-throughput live-imaging of embryos in microwell arrays using a modular specimen mounting system
    Seth Donoughe, Chiyoung Kim, Cassandra G. Extavour
    Biology Open 2018 7: bio031260 doi: 10.1242/bio.031260 Published 9 July 2018

    Summary: This Methods & Techniques article describes a customizable device for mounting and live-imaging a wide range of tissues and species; complete design files and instructions for assembly are included.

  • RESEARCH ARTICLE
    The teneurin C-terminal domain possesses nuclease activity and is apoptogenic
    Jacqueline Ferralli, Richard P. Tucker, Ruth Chiquet-Ehrismann
    Biology Open 2018 7: bio031765 doi: 10.1242/bio.031765 Published 19 March 2018

    Summary: Teneurins are transmembrane proteins found in the developing nervous system that are related to bacterial toxins. Teneurins also have cytotoxic properties that may help regulate apoptosis or pruning.

  • RESEARCH ARTICLE
    Light regimes differentially affect baseline transcript abundance of stress-axis and (neuro)development-related genes in zebrafish (Danio rerio, Hamilton 1822) AB and TL larvae
    Ruud van den Bos, Jan Zethof, Gert Flik, Marnix Gorissen
    Biology Open 2017 6: 1692-1697; doi: 10.1242/bio.028969

    Summary: This study shows gene expression levels of zebrafish AB and TL larvae differ in relation to light regimes, strengthening earlier observations: AB and TL are not interchangeable strains.

  • RESEARCH ARTICLE
    Fat-containing cells are eliminated during Dictyostelium development
    Jessica M. Kornke, Markus Maniak
    Biology Open 2017 6: 1294-1304; doi: 10.1242/bio.025478

    Summary: In contrast to many living organisms, storage fat is not beneficial for Dictyostelium cells when progressing through starvation and subsequent development of a dormant stage.

  • RESEARCH ARTICLE
    The role of nitric oxide during embryonic epidermis development of Xenopus laevis
    Silvie Tomankova, Pavel Abaffy, Radek Sindelka
    Biology Open 2017 6: 862-871; doi: 10.1242/bio.023739

    Summary: Embryonic epidermis development is influenced by nitric oxide, where it has been linked to the development of ionocytes, multi-ciliated cells and small secretory cells.

  • RESEARCH ARTICLE
    Morphology and cardiac physiology are differentially affected by temperature in developing larvae of the marine fish mahi-mahi (Coryphaena hippurus)
    Prescilla Perrichon, Christina Pasparakis, Edward M. Mager, John D. Stieglitz, Daniel D. Benetti, Martin Grosell, Warren W. Burggren
    Biology Open 2017 6: 800-809; doi: 10.1242/bio.025692

    Summary: Acute and chronic temperature exposures affect differentially heart rate, stroke volume and cardiac output in mahi-mahi (Coryphaena hippurus) during early development.

  • RESEARCH ARTICLE
    A role for planar cell polarity during early endoderm morphogenesis
    Lee B. Miles, Takamasa Mizoguchi, Yutaka Kikuchi, Heather Verkade
    Biology Open 2017 6: 531-539; doi: 10.1242/bio.021899

    Summary: Here we characterise endodermal morphogenesis during somitogenesis stages, and show that PCP signalling plays a mixed role in endoderm development during these stages.

  • RESEARCH ARTICLE
    Chicken muscle mitochondrial content appears co-ordinately regulated and is associated with performance phenotypes
    Antonio Reverter, Ron Okimoto, Robyn Sapp, Walter G. Bottje, Rachel Hawken, Nicholas J. Hudson
    Biology Open 2017 6: 50-58; doi: 10.1242/bio.022772

    Summary: We have detected variation in muscle mitochondrial content across chickens. This variation relates to phenotypes and also indicates coordinate regulation of mitochondrial biogenesis across the musculature.

Pages

  • Next
  • 1
  • 2
  • 3

Other subject collections

Articles

  • Accepted manuscripts
  • Issue in progress
  • Latest complete issue
  • Issue archive
  • Archive by article type
  • Interviews
  • Sign up for alerts

About us

  • About BiO
  • Editors and Board
  • Editor biographies
  • Grants and funding
  • Workshops and Meetings
  • The Company of Biologists

For Authors

  • Submit a manuscript
  • Aims and scope
  • Presubmission enquiries
  • Article types
  • Manuscript preparation
  • Cover suggestions
  • Editorial process
  • Promoting your paper
  • Open Access
  • Biology Open transfer option

Journal Info

  • Journal policies
  • Rights and permissions
  • Media policies
  • Reviewer guide
  • Sign up for alerts

Contact

  • Contact BiO
  • Advertising
  • Feedback

Twitter   YouTube   LinkedIn

© 2019   The Company of Biologists Ltd   Registered Charity 277992