Development
- High-throughput live-imaging of embryos in microwell arrays using a modular specimen mounting system
Summary: This Methods & Techniques article describes a customizable device for mounting and live-imaging a wide range of tissues and species; complete design files and instructions for assembly are included.
- The teneurin C-terminal domain possesses nuclease activity and is apoptogenic
Summary: Teneurins are transmembrane proteins found in the developing nervous system that are related to bacterial toxins. Teneurins also have cytotoxic properties that may help regulate apoptosis or pruning.
- Light regimes differentially affect baseline transcript abundance of stress-axis and (neuro)development-related genes in zebrafish (Danio rerio, Hamilton 1822) AB and TL larvae
Summary: This study shows gene expression levels of zebrafish AB and TL larvae differ in relation to light regimes, strengthening earlier observations: AB and TL are not interchangeable strains.
- Fat-containing cells are eliminated during Dictyostelium development
Summary: In contrast to many living organisms, storage fat is not beneficial for Dictyostelium cells when progressing through starvation and subsequent development of a dormant stage.
- The role of nitric oxide during embryonic epidermis development of Xenopus laevis
Summary: Embryonic epidermis development is influenced by nitric oxide, where it has been linked to the development of ionocytes, multi-ciliated cells and small secretory cells.
- Morphology and cardiac physiology are differentially affected by temperature in developing larvae of the marine fish mahi-mahi (Coryphaena hippurus)
Summary: Acute and chronic temperature exposures affect differentially heart rate, stroke volume and cardiac output in mahi-mahi (Coryphaena hippurus) during early development.
- A role for planar cell polarity during early endoderm morphogenesis
Summary: Here we characterise endodermal morphogenesis during somitogenesis stages, and show that PCP signalling plays a mixed role in endoderm development during these stages.
- Chicken muscle mitochondrial content appears co-ordinately regulated and is associated with performance phenotypes
Summary: We have detected variation in muscle mitochondrial content across chickens. This variation relates to phenotypes and also indicates coordinate regulation of mitochondrial biogenesis across the musculature.
- Genetic basis of hindlimb loss in a naturally occurring vertebrate model
Summary: Here we genetically characterise mutations in tbx4 which underlie pelvic finless, a naturally occurring model of hindlimb loss in zebrafish that lacks pelvic fin structures.
- On the development of extragonadal and gonadal human germ cells
Summary: The presence and developmental trajectory of ectopic human germ cells in the adrenals and gonads during the first and second trimesters is investigated by comparing the expression dynamics of early, late and meiotic germ cell markers.