- IF-combined smRNA FISH reveals interaction of MCPIP1 protein with IER3 mRNA
Summary: We identify IER3 mRNA as a newly discovered MCPIP1 target using recently described IF-based procedures, and also identify a conserved element involved in MCPIP1-dependent IER3 transcript destabilization.
- Biosignature for airway inflammation in a house dust mite-challenged murine model of allergic asthma
Summary: This study describes a systematic analysis of molecular end points in an murine model of allergic asthma. The biosignature described can be used to interrogate molecular mechanisms and intervention strategies for airway inflammation pertinent to allergic asthma that precedes and possibly potentiates airway remodeling and fibrosis.