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inner ear

  • RESEARCH ARTICLE
    Tbx1 and Jag1 act in concert to modulate the fate of neurosensory cells of the mouse otic vesicle
    Stephania Macchiarulo, Bernice E. Morrow
    Biology Open 2017 6: 1472-1482; doi: 10.1242/bio.027359

    Summary: Normal dosages of Tbx1 and Jag1 are required to maintain a proper balance of cell types within the neurosensory domain of the otic vesicle to form the inner ear.

  • RESEARCH ARTICLE
    Dlx3b/4b is required for early-born but not later-forming sensory hair cells during zebrafish inner ear development
    Simone Schwarzer, Sandra Spieß, Michael Brand, Stefan Hans
    Biology Open 2017 6: 1270-1278; doi: 10.1242/bio.026211

    Summary: The transcription factors Dlx3b and Dlx4b control the formation of early-born sensory hair cells or tether cells in the developing zebrafish inner ear.

  • RESEARCH ARTICLE
    Surviving murine experimental sepsis affects the function and morphology of the inner ear
    Natalie Fischer, Nina Maria Mathonia, Georges Hollerich, Julian Veser, Leyla Pinggera, Daniel Dejaco, Rudolf Glueckert, Anneliese Schrott-Fischer, Peter Lackner, Herbert Riechelmann, Joachim Schmutzhard
    Biology Open 2017 6: 732-740; doi: 10.1242/bio.024588

    Summary: This study shows that a mild sepsis leads to a significant hearing impairment due to apoptosis of different inner ear structures.

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