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For more information on measures BiO is taking to support the community at this time, please see here.
Biology Open (BiO) is an online Open Access journal that supports the community of biologists through the publication of peer-reviewed original research across all aspects of the biological sciences. We aim to provide rapid peer review and publication of scientifically sound results and conclusions, without a requirement for perceived impact. BiO also aspires to promote a peer-review system that is timely, thorough, constructive and fair.
Authors are encouraged to submit work of appropriate scope directly to BiO. Editorial decisions are made by an international board of research-active academic Editors, led by Editor-in-Chief Steven Kelly and supported by Deputy Editors Cathy Jackson and Yishi Jin.
Recent articles
Three-dimensional model of glioblastoma by co-culturing tumor stem cells with human brain organoids
Roberta Azzarelli, Michela Ori, Anna Philpott, Benjamin D. Simons
Azzarelli and colleagues describe a method for co-culturing glioblastoma stem cells with human cerebral organoids in order to model tumour complexity and recapitulate cellular heterogeneity in vitro.
Tetraspanin18 regulates angiogenesis through VEGFR2 and Notch pathways
Grace X. Li, Shaobing Zhang, Ren Liu, Bani Singh, Sukhmani Singh, David I. Quinn, Gage Crump, Parkash S. Gill
Tspan18 is a transmembrane protein with highly restricted expression in endothelial cells; it acts as a crucial regulator of the VEGF and Notch pathways. The authors show that it regulates artery–vein specification, vessel patterning and vessel stability.
Future Leader Reviews
Cardiac myosin super relaxation (SRX): a perspective on fundamental biology, human disease and therapeutics
Manuel Schmid, Christopher N. Toepfer
A new Future Leader Review by Manuel Schmid and Christopher Toepfer discusses the rapidly-expanding field of myosin super relaxation in the context of cardiovascular disease. Read the full article and their accompanying interview.
Find out more about our Future Leader Reviews – an exclusive opportunity for early-career researchers who want to establish themselves in their field. Previously published Future Leader Reviews can be found here.
News from BiO
Highlighted articles
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Noor A. Al-Maslamani, Abdulghani A. Khilan, Henning F. Horn
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Chance E. Jones, Susan L. Forsburg
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Roberta Azzarelli, Michela Ori, Anna Philpott, Benjamin D. Simons
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Jeffrey D. Hildebrand, Adam D. Leventry, Omoregie P. Aideyman, John C. Majewski, James A. Haddad, Dawn C. Bisi, Nancy Kaufmann
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Anupam Bhoi, Francesca Palladino, Paola Fabrizio
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Katherine K. Slemmons, Michael D. Deel, Yi-Tzu Lin, Kristianne M. Oristian, Nina Kuprasertkul, Katia C. Genadry, Po-Han Chen, Jen-Tsan Ashley Chi, Corinne M. Linardic
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Xin Huang, Sijia Wang, Li Jin, Yungang He
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Jaeike W. Faber, Jaco Hagoort, Antoon F. M. Moorman, Vincent M. Christoffels, Bjarke Jensen
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Minglin Ou, Min Zhao, Chunhong Li, Donge Tang, Yong Xu, Weier Dai, Weiguo Sui, Yue Zhang, Zhen Xiang, Chune Mo, Hua Lin, Yong Dai
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Manuela Santalla, Lucía Pagola, Ivana Gómez, Darío Balcazar, Carlos A. Valverde, Paola Ferrero
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Venkatesh Nagarajan-Radha, Paramanantha Swami Doss Devaraj
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Marina Hosotani, Teppei Nakamura, Osamu Ichii, Takao Irie, Yuji Sunden, Yaser Hosny Ali Elewa, Takafumi Watanabe, Hiromi Ueda, Takashi Mishima, Yasuhiro Kon
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Grace X. Li, Shaobing Zhang, Ren Liu, Bani Singh, Sukhmani Singh, David I. Quinn, Gage Crump, Parkash S. Gill
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Aitana M. Castro Colabianchi, María B. Tavella, Laura E. Boyadjián López, Marcelo Rubinstein, Lucía F. Franchini, Silvia L. López
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Zhuoling An, Chen Shi, Pengfei Li, Lihong Liu