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Research Article
Mutations in the splicing regulator Prp31 lead to retinal degeneration in Drosophila
Sarita Hebbar, Malte Lehmann, Sarah Behrens, Catrin Hälsig, Weihua Leng, Michaela Yuan, Sylke Winkler, Elisabeth Knust
Biology Open 2021 10: bio052332 doi: 10.1242/bio.052332 Published 25 January 2021
Sarita Hebbar
Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
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  • ORCID record for Sarita Hebbar
Malte Lehmann
Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
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Sarah Behrens
Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
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Catrin Hälsig
Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
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Weihua Leng
Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
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Michaela Yuan
Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
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Sylke Winkler
Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
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Elisabeth Knust
Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
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  • For correspondence: knust@mpi-cbg.de
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Article Information

vol. 10 no. 1, bio052332

DOI 
https://doi.org/10.1242/bio.052332
PubMed 
33495354

Published By 
The Company of Biologists Ltd
Online ISSN 
2046-6390
History 
  • Received May 26, 2020
  • Accepted December 1, 2020
  • Published online January 25, 2021.
Copyright & Usage 
© 2021. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.


Author Information

  1. Sarita Hebbar*,
  2. Malte Lehmann*,‡,
  3. Sarah Behrens§,
  4. Catrin Hälsig,
  5. Weihua Leng,
  6. Michaela Yuan,
  7. Sylke Winkler and
  8. Elisabeth Knust¶
  1. Max-Planck-Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
  1. ↵¶Author for correspondence (knust{at}mpi-cbg.de)
  • ↵* These authors contributed equally to this work

  • ↵‡ Present address: Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Campus Benjamin Franklin. Medical Department, Division of Gastroenterology, Infectiology and Rheumatology (including Nutritional Medicine), Hindenburgdamm 30, 12200 Berlin, Germany.

  • ↵§ Present address: Novartis Pharma Stein AG, Schaffhauserstrasse, 4332 Stein, Switzerland.

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Keywords

  • Spliceosome
  • Photoreceptor cells
  • Rhodopsin
  • scarlet
  • twinfilin

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Research Article
Mutations in the splicing regulator Prp31 lead to retinal degeneration in Drosophila
Sarita Hebbar, Malte Lehmann, Sarah Behrens, Catrin Hälsig, Weihua Leng, Michaela Yuan, Sylke Winkler, Elisabeth Knust
Biology Open 2021 10: bio052332 doi: 10.1242/bio.052332 Published 25 January 2021
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Research Article
Mutations in the splicing regulator Prp31 lead to retinal degeneration in Drosophila
Sarita Hebbar, Malte Lehmann, Sarah Behrens, Catrin Hälsig, Weihua Leng, Michaela Yuan, Sylke Winkler, Elisabeth Knust
Biology Open 2021 10: bio052332 doi: 10.1242/bio.052332 Published 25 January 2021

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