Cover article – A solution to prevent secondary flow in adherent cell cultures

Peter Szaraz and his colleagues show that, although secondary flow in small scale cultures can crucially affect cell phenotype and function, a simple modification of the classical round-shaped cell culture vessels can minimize the adverse effect of secondary flow.

Josh Currie, Tatiana Sandoval-Guzmán and their co-workers study dermal Prrx1 enhancer-positive cells, which are injury-responsive fibroblasts, and demonstrate that they readily migrate into the wound bed and amplify on average 16-fold beyond their uninjured numbers.

Have you seen our interviews with the early-career first authors of our papers? Recently, we caught up with first authors Peter Szaraz, Josh Currie, Jeanette C. Perron, Louise Roberts and Qingting Hu.

Biology Open has strong credentials and publishing with us is easy and fast. BiO aims to provide rapid publication for scientifically sound observations and valid conclusions in developmental, cell, experimental and translational biology. Submit your paper here – you’ll be in good company!

Recent disease mechanism highlights in BiO – Bernhard Weber and his team find that mice carrying the human Y227N mutation in the endogenous Best1 gene reveal a pathologic phenotype in testis. This provides an in vivo tool to evaluate therapeutic efficacies aimed at restoring protein function.

Transfer to Biology Open

Did you know: if your submission to one of our sister journals, Development, Journal of Cell Science, Journal of Experimental Biology or Disease Models & Mechanisms, is unsuccessful, you can transfer your paper and any reviews directly to Biology Open! The majority of papers transferred with reviews are accepted for publication. Read here to find out more.

BiO partners with Publons!

Biology Open is pleased to announce a new partnership with Publons! This allows reviewers to easily track and verify every review by choosing to add the review to their Publons profile when completing the review submission form. Publons makes it simple for reviewers to showcase their peer review contributions in a format that can be included in job and funding applications (without breaking reviewer anonymity). Read the official announcement here!

preLights - Cross-kingdom recognition of bacterial small RNAs induces transgenerational pathogenic avoidance

Madhuja Samaddar highlights a preprint from Coleen Murphy’s lab, which uncovers how C. elegans pass on a learned avoidance of pathogenic Pseudomonas aeruginosa to four generations of its progeny!