Cover image
Planarian flatworms have the remarkable capacity to regenerate their entire body. Despite a wealth of molecular-genetic data, no constructive model of regenerative patterning exists. Levin and colleagues (doi:10.1242/bio.20123400) created a formalism for abstracting key features of flatworm anatomy from functional experimental data; an example of this graph representation is shown here superimposed upon successive stages of head regeneration in an amputated worm. New artificial intelligence tools can use the formalism and database to help derive algorithmic models of regeneration, establishing a new bioinformatics of shape.
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Biology Open and COVID-19
We are aware that the COVID-19 pandemic is having an unprecedented impact on researchers worldwide. The Editors of all The Company of Biologists’ journals have been considering ways in which we can alleviate concerns that members of our community may have around publishing activities during this time. Read about the actions we are taking at this time.
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It’s a time of turmoil for young scientists
“My students are my priority – they are on the brink of their careers.”
Dr Jodie Rummer (ARC Centre of Excellence for Coral Reef Studies at James Cook University) talks about the importance of her role as a supervisor in supporting graduate students and post docs financially, intellectually and emotionally during this period of uncertainty.
Gap junctions: historical discoveries and new findings in the C. elegans nervous system
Following the announcement of Biology Open’s new Future Leader Review articles, we are thrilled to publish our first one! Jin, Park, Lyu et al. highlight the diverse roles of gap junctions and innexins in the C. elegans nervous system, contributing to fundamental understanding of gap junctions in all animals.
Interview - Jessica Kabutomori
First author Jessica Kabutomori talks about her latest paper in BiO, which investigates murine urea transporters, sharing the biggest surprise of her work and what she has planned for the future.