Cover image
Lateral view of the retina of zebrafish transgenic line Tg(h2afv:GFP; EF1α:mCherry-zGem). Using this transgenic line, three cell-cycle phases, G1, S/G2, and M, are distinguishable. Cells undergoing G1 and G2/M phases express GFP and mCherry fluorescence, respectively. Cells in M phase express a high level of mCherry fluorescence with condensed GFP. The authors used this transgenic line and investigated cell proliferation and cell division in zebrafish lens epithelium. They found that cell proliferation and cell-division orientation are spatially regulated in zebrafish lens epithelium, and that a cell adhesion molecule, E-cadherin, is required for the spatial pattern of cell-division orientation. See the article by Mochizuki et al. (doi: 10.1242/bio.20149563).
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Biology Open and COVID-19
We are aware that the COVID-19 pandemic is having an unprecedented impact on researchers worldwide. The Editors of all The Company of Biologists’ journals have been considering ways in which we can alleviate concerns that members of our community may have around publishing activities during this time. Read about the actions we are taking at this time.
Please don’t hesitate to contact the Editorial Office if you have any questions or concerns.
Future Leader Review - Cardiac myosin super relaxation
A new Future Leader Review by Manuel Schmid and Christopher Toepfer discusses the rapidly-expanding field of myosin super relaxation in the context of cardiovascular disease. Read the full Review and their accompanying interview.
Find out more about our Future Leader Reviews – they are an exclusive opportunity for early-career researchers who want to establish themselves in their field.
An interview with Roberta Azzarelli
In an interview, first author Roberta Azzarelli discusses her 3D model of glioblastoma and shares her thoughts on how to improve the professional lives of early-career researchers: formal mentorship programmes, a clearly structured career path and taking part in initiatives such as the Node Network.
News from our sister journals
Development continues to run a successful new webinar series, Development presents…, while Journal of Cell Science has recently welcomed Esperanza Agullo-Pascual as FocalPlane’s new Community Manager. Journal of Experimental Biology’s new special issue highlights the role of comparative biology in tackling climate change and Liz Patton, the new Editor-in-Chief of Disease Models & Mechanisms, sets out her visions and priorities.