Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Interviews
    • Sign up for alerts
  • About us
    • About BiO
    • Editors and Board
    • Editor biographies
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact BiO
    • Advertising
    • Feedback
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

User menu

  • Log in

Search

  • Advanced search
Biology Open
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

supporting biologistsinspiring biology

Biology Open

Advanced search

RSS   Twitter   Facebook   YouTube

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Interviews
    • Sign up for alerts
  • About us
    • About BiO
    • Editors and Board
    • Editor biographies
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact BiO
    • Advertising
    • Feedback

 

  You have access

  Open access

November, 2016; 5 (11)

RESEARCH ARTICLES

  • Open Access
    Morphological diversity of blastula formation and gastrulation in temnopleurid sea urchins
    Chisato Kitazawa, Tsubasa Fujii, Yuji Egusa, Miéko Komatsu, Akira Yamanaka
    Biology Open 2016 5: 1555-1566; doi: 10.1242/bio.019018

    Summary: Closely related temnopleurid sea urchins exhibit diversity in blastula formation and gastrulation during early morphogenesis.

  • Open Access
    Regulatory effects of electronic beam irradiation on mir-21/smad7-mediated collagen I synthesis in keloid-derived fibroblasts
    Shifeng Li, Wei Liu, Ying Lei, Jianhong Long
    Biology Open 2016 5: 1567-1574; doi: 10.1242/bio.018770

    Summary: Using primary keloid-derived fibroblasts, we demonstrate that electronic beam irradiation inhibits the recurrence of keloid scarring by suppressing collagen I expression via mir-21/smad7-mediated p38 activation.

  • Open Access
    Skeletal muscle growth dynamics and the influence of first-feeding diet in Atlantic cod larvae (Gadus morhua L.)
    Tu A. Vo, Trina F. Galloway, Tora Bardal, Christine K. Halseth, Gunvor Øie, Elin Kjørsvik
    Biology Open 2016 5: 1575-1584; doi: 10.1242/bio.018556

    Summary: Hyperplastic and hypertrophic growth dynamics of red and white muscle were strongly related to cod larval size and corresponded with the metamorphosis process. First-feeding diet quality can prolong effects on muscle growth potential in cod larvae.

  • Open Access
    Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development
    Dalya Ataca, Marian Caikovski, Alessandra Piersigilli, Alexandre Moulin, Charaf Benarafa, Sarah E. Earp, Yakir Guri, Corinne Kostic, Yvan Arsenijevic, Raija Soininen, Suneel S. Apte, Cathrin Brisken
    Biology Open 2016 5: 1585-1594; doi: 10.1242/bio.019711

    Summary: We generated mice deficient for the secreted protease ADAMTS18 implicated in human disease and show that the gene is required in the development of the lens, lung, and the female reproductive tract.

  • Open Access
    Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression
    Avinash V. Dharmadhikari, Jenny J. Sun, Krzysztof Gogolewski, Brandi L. Carofino, Vladimir Ustiyan, Misty Hill, Tadeusz Majewski, Przemyslaw Szafranski, Monica J. Justice, Russell S. Ray, Mary E. Dickinson, Vladimir V. Kalinichenko, Anna Gambin, Paweł Stankiewicz
    Biology Open 2016 5: 1595-1606; doi: 10.1242/bio.019208

    Summary: Similar to Foxf1 loss, Foxf1 overexpression in mice is lethal. This finding highlights the need to consider alternatives beyond gene therapy to find a cure for alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV).

  • Open Access
    Alternative exon usage creates novel transcript variants of tumor suppressor SHREW-1 gene with differential tissue expression profile
    Petra A. B. Klemmt, Eduard Resch, Isabell Smyrek, Knut Engels, Ernst H. K. Stelzer, Anna Starzinski-Powitz
    Biology Open 2016 5: 1607-1619; doi: 10.1242/bio.019463

    Summary: Transcripts of the tumor suppressor gene SHREW-1 exist in various splice variants in human and mouse encoding proteins with a differential expression and intracellular localization profile.

  • Open Access
    Directional cell movements downstream of Gbx2 and Otx2 control the assembly of sensory placodes
    Ben Steventon, Roberto Mayor, Andrea Streit
    Biology Open 2016 5: 1620-1624; doi: 10.1242/bio.020966

    Summary: Using spatial and temporally controlled perturbations followed by live cell tracking in vivo, this paper demonstrates that directional movements downstream of Gbx2 and Otx2 are important for otic and lens placode formation.

  • Open Access
    Establishment of a novel retinoblastoma (Rb) nude mouse model by intravitreal injection of human Rb Y79 cells – comparison of in vivo analysis versus histological follow up
    Alexander V. Tschulakow, Ulrich Schraermeyer, H. Peter Rodemann, Sylvie Julien-Schraermeyer
    Biology Open 2016 5: 1625-1630; doi: 10.1242/bio.019976

    Summary: We present a novel retinoblastoma nude xenograft mouse model which closely resembles the human disease and allows broad application possibilities and a comparison of in vivo and histological analysis.

  • Open Access
    MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus
    Barbara Vacca, Elena Sanchez-Heras, Emily Steed, Maria S. Balda, Shin-Ichi Ohnuma, Noriaki Sasai, Roberto Mayor, Karl Matter
    Biology Open 2016 5: 1631-1641; doi: 10.1242/bio.018945

    Summary: MarvelD3 regulates eye morphogenesis through modulation of the JNK pathway, eye-field specification and the balance between cell proliferation and survival.

  • Open Access
    Oviposition preferences for ethanol depend on spatial arrangement and differ dramatically among closely related Drosophila species
    Matt Sumethasorn, Thomas L. Turner
    Biology Open 2016 5: 1642-1647; doi: 10.1242/bio.019380

    Summary: Drosophila species make dramatically different egg-laying decisions depending on ethanol concentration and the distances between options. Surprisingly, we find that the species with the lowest ethanol tolerance prefers ethanol the most.

  • Open Access
    Ecdysone signaling induces two phases of cell cycle exit in Drosophila cells
    Yongfeng Guo, Kerry Flegel, Jayashree Kumar, Daniel J. McKay, Laura A. Buttitta
    Biology Open 2016 5: 1648-1661; doi: 10.1242/bio.017525

    Summary: Pulsed ecdysone signaling remodels cell cycle dynamics, causing distinct primary and secondary cell cycle arrests in Drosophila cells, analogous to those observed in the wing during metamorphosis.

  • Open Access
    Eyes shut homolog is required for maintaining the ciliary pocket and survival of photoreceptors in zebrafish
    Miao Yu, Yu Liu, Jing Li, Brianna N. Natale, Shuqin Cao, Dongliang Wang, Jeffrey D. Amack, Huaiyu Hu
    Biology Open 2016 5: 1662-1673; doi: 10.1242/bio.021584

    Summary: The extracellular matrix protein Eyes shut homolog is required for maintaining the integrity of the ciliary pocket and survival of photoreceptors in zebrafish.

  • Open Access
    A novel mutation in the N-terminal domain of Drosophila BubR1 affects the spindle assembly checkpoint function of BubR1
    Marie Duranteau, Jean-Jacques Montagne, Zohra Rahmani
    Biology Open 2016 5: 1674-1679; doi: 10.1242/bio.021196

    Summary: We have identified a novel short motif sequence in the Drosophila BubR1 protein which when mutated affects the amount of Cdc20 recruited to the kinetochores and leads to an abrogation of the SAC.

  • Open Access
    Heterotypic interactions regulate cell shape and density during color pattern formation in zebrafish
    Prateek Mahalwar, Ajeet Pratap Singh, Andrey Fadeev, Christiane Nüsslein-Volhard, Uwe Irion
    Biology Open 2016 5: 1680-1690; doi: 10.1242/bio.022251

    Summary: The conspicuous pigmentation pattern of zebrafish is produced by three kinds of interacting pigment cells. Here we address the cellular consequences of these interactions in wild-type fish and mutants with altered pigment patterns.

  • Open Access
    Calcium homeostasis alterations in a mouse model of the Dynamin 2-related centronuclear myopathy
    Bodvaël Fraysse, Pascale Guicheney, Marc Bitoun
    Biology Open 2016 5: 1691-1696; doi: 10.1242/bio.020263

    Summary: Dynamin 2 mutations cause centronuclear myopathy via unclear mechanisms. We show in a mouse model that changes in cytosolic calcium via incorrect membrane permeability correlate with muscle weakness.

  • Open Access
    Identification of a novel putative interaction partner of the nucleoporin ALADIN
    Ramona Jühlen, Dana Landgraf, Angela Huebner, Katrin Koehler
    Biology Open 2016 5: 1697-1705; doi: 10.1242/bio.021162

    Summary: We report the interaction of the microsomal integral membrane protein progesterone receptor membrane component 2 with the nucleoporin ALADIN at the perinuclear ER and nuclear envelope.

  • Open Access
    The impact of FOXO on dopamine and octopamine metabolism in Drosophila under normal and heat stress conditions
    Nataly E. Gruntenko, Natalya V. Adonyeva, Elena V. Burdina, Evgenia K. Karpova, Olga V. Andreenkova, Daniil V. Gladkikh, Yury Y. Ilinsky, Inga Yu Rauschenbach
    Biology Open 2016 5: 1706-1711; doi: 10.1242/bio.022038

    Summary: The transcription factor FOXO affects catecholamine metabolism under normal and heat stress conditions in D. melanogaster, and juvenile hormone (JH) is a mediator of this effect.

  • Open Access
    Hygienic behaviour in Brazilian stingless bees
    Hasan Al Toufailia, Denise A. Alves, José M. S. Bento, Luis C. Marchini, Francis L. W. Ratnieks
    Biology Open 2016 5: 1712-1718; doi: 10.1242/bio.018549

    Summary: Hygienic behaviour such as the removal of dead and diseased larvae and pupae has an important role in colony health in stingless bees, and it is greater than in unselected honey bee populations

  • Open Access
    Effects of Hd2 in the presence of the photoperiod-insensitive functional allele of Hd1 in rice
    Zhen-Hua Zhang, Li-Yong Cao, Jun-Yu Chen, Ying-Xin Zhang, Jie-Yun Zhuang, Shi-Hua Cheng
    Biology Open 2016 5: 1719-1726; doi: 10.1242/bio.021071

    Summary: We show that photoperiod-insensitive components of alleles of Hd1 and Hd2 play an important role in balancing ecological adaptability and high-yield accumulation in rice.

  • Open Access
    Expression of Cucumber mosaic virus suppressor 2b alters FWA methylation and its siRNA accumulation in Arabidopsis thaliana
    Sadia Hamera, Youngsheng Yan, Xiaoguang Song, Safee Ullah Chaudhary, Iram Murtaza, Lei Su, Muhammad Tariq, Xiaoying Chen, Rongxiang Fang
    Biology Open 2016 5: 1727-1734; doi: 10.1242/bio.017244

    Summary: CMV suppressor 2b perturbs host defense by interrupting epigenetic signaling. 2b causes FWA siRNAs sequestration and hypo-methylation of FWA promoter region. It shines light on a hitherto little understood mechanism of viral suppression of host epigenetics.

  • Open Access
    Environment-dependent prey capture in the Atlantic mudskipper (Periophthalmus barbarus)
    K. B. Michel, P. Aerts, S. Van Wassenbergh
    Biology Open 2016 5: 1735-1742; doi: 10.1242/bio.019794

    Summary: A comparison of the kinematics of aquatic and terrestrial feeding in the mudskipper shows how the ancestral kinematic pattern of aquatic feeding is modified to enable the terrestrial capture of prey.

METHODS & TECHNIQUES

  • Open Access
    Energy metabolic state in hypothermically stored boar spermatozoa using a revised protocol for efficient ATP extraction
    Quynh Thu Nguyen, Ulrike Wallner, Marion Schmicke, Dagmar Waberski, Heiko Henning
    Biology Open 2016 5: 1743-1751; doi: 10.1242/bio.017954

    Summary: A revised protocol for efficient extraction of ATP from boar spermatozoa is presented that consistently yields high ATP contents and energy charge values from fresh and frozen samples.

  • Open Access
    A portable infrared photoplethysmograph: heartbeat of Mytilus galloprovincialis analyzed by MRI and application to Bathymodiolus septemdierum
    Eriko Seo, Toshiyuki Sazi, Morio Togawa, Osamu Nagata, Masataka Murakami, Shigeaki Kojima, Yoshiteru Seo
    Biology Open 2016 5: 1752-1757; doi: 10.1242/bio.020909

    Summary: Infrared photoplethysmogram of Mytilus heart was analyzed by magnetic resonance imaging. Portable photoplethysmographs provide a noninvasive, economical and robust method to monitor the heartbeat of mussels in field experiments.

Back to top
PreviousNext
Previous IssueNext Issue

This issue

Biology Open: 5 (11)
  • Table of Contents (PDF)
  • About the Cover
  • Table of Contents
  • Index by author
  • Issue info (PDF)

RSSRSS Icon

JUMP TO

  • RESEARCH ARTICLES
  • METHODS & TECHNIQUES

  Alert me to new issues of Biology Open

  • Accepted manuscripts
  • Most-read
Loading
  • Open Access

    Avoiding being stung or bitten – prey capture behaviors of the ant-eating Texas horned lizard (Phrynosoma cornutum)

    Ismene Fertschai, Wade C. Sherbrooke, Matthias Ott, Boris P. Chagnaud
    PDF
  • Open Access

    A Zebrafish Forward Genetic Screen Identifies an Indispensible Threonine Residue in the Kinase Domain of PRKD2

    Panagiota Giardoglou, Despina Bournele, Misun Park, Stavroula Kanoni, George V. Dedoussis, Susan F. Steinberg, Panos Deloukas, Dimitris Beis
    PDF
  • Open Access

    Interdomain interactions regulate the localization of a lipid transfer protein at ER-PM contact sites

    Bishal Basak, Harini Krishnan, Raghu Padinjat
    PDF
  • Open Access

    Conditional targeting of phosphatidylserine decarboxylase to lipid droplets

    Santosh Kumar, Chandramohan Chitraju, Robert Farese, Tobias Walther, Christopher G. Burd
    PDF
  • Open Access

    The thermal dependence and molecular basis of physiological color change in Takydromus septentrionalis (Lacertidae)

    Kun Guo, Jun Zhong, Lin Zhu, Fan Xie, Yu Du, Xiang Ji
    PDF
See more accepted manuscripts...

Other journals from The Company of Biologists

Development

Journal of Cell Science

Journal of Experimental Biology

Disease Models & Mechanisms

Advertisement

Biology Open and COVID-19

We are aware that the COVID-19 pandemic is having an unprecedented impact on researchers worldwide. The Editors of all The Company of Biologists’ journals have been considering ways in which we can alleviate concerns that members of our community may have around publishing activities during this time. Read about the actions we are taking at this time.

Please don’t hesitate to contact the Editorial Office if you have any questions or concerns.


New funding scheme supports sustainable events

As part of our Sustainable Conferencing Initiative, we are pleased to announce funding for organisers that seek to reduce the environmental footprint of their event. The next deadline to apply for a Scientific Meeting grant is 26 March 2021.


Future Leader Review – early neurodegeneration of Alzheimer’s disease

A new Future Leader Review from Olayemi Olajide, Marcus Suvanto and Clifton Andrew Chapman evaluates the molecular mechanisms that may explain the vulnerability and susceptibility of the entorhinal cortex to early neurodegeneration during the pathogenesis of Alzheimer's disease.

Find out more about our Future Leader Reviews – they are an exclusive opportunity for early-career researchers who want to establish themselves in their field.


First author interviews

Catch up on our latest first author interviews to go behind the scenes of our latest research, find out more about the authors and hear from early-career researchers themselves how they’re finding life at the bench.


Retinal degeneration in Drosophila

Thank you to Elisabeth Knust and her team for their confocal image of a longitudinal section of an adult Drosophila retina, which brightens the cover of our latest issue. Read the research behind the cover.

Articles

  • Accepted manuscripts
  • Issue in progress
  • Latest complete issue
  • Issue archive
  • Archive by article type
  • Interviews
  • Sign up for alerts

About us

  • About BiO
  • Editors and Board
  • Editor biographies
  • Grants and funding
  • Journal Meetings
  • Workshops
  • The Company of Biologists

For Authors

  • Submit a manuscript
  • Aims and scope
  • Presubmission enquiries
  • Article types
  • Manuscript preparation
  • Cover suggestions
  • Editorial process
  • Promoting your paper
  • Open Access

Journal Info

  • Journal policies
  • Rights and permissions
  • Media policies
  • Reviewer guide
  • Sign up for alerts

Contact

  • Contact BiO
  • Advertising
  • Feedback

Twitter   YouTube   LinkedIn

© 2021   The Company of Biologists Ltd   Registered Charity 277992