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Research Article
Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis
Assunta Liberti, Ivana Zucchetti, Daniela Melillo, Diana Skapura, Yoshimi Shibata, Rosaria De Santis, Maria Rosaria Pinto, Gary W. Litman, Larry J. Dishaw
Biology Open 2018 7: bio029355 doi: 10.1242/bio.029355 Published 17 January 2018
Assunta Liberti
1Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy
2University of South Florida, Morsani College of Medicine, Department of Pediatrics, Tampa, FL 33606, USA
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  • ORCID record for Assunta Liberti
  • For correspondence: ldishaw@health.usf.edu libertia@mail.usf.edu
Ivana Zucchetti
1Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy
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Daniela Melillo
1Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy
3Institute of Protein Biochemistry (IBP), National Research Council (CNR), Napoli 80131, Italy
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Diana Skapura
4Molecular Genetics, Johns Hopkins All Children's Hospital, Saint Petersburg, FL 33701, USA
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Yoshimi Shibata
5Biomedical Science Department, Florida Atlantic University, Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA
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Rosaria De Santis
1Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy
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Maria Rosaria Pinto
1Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy
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Gary W. Litman
2University of South Florida, Morsani College of Medicine, Department of Pediatrics, Tampa, FL 33606, USA
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Larry J. Dishaw
2University of South Florida, Morsani College of Medicine, Department of Pediatrics, Tampa, FL 33606, USA
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  • ORCID record for Larry J. Dishaw
  • For correspondence: ldishaw@health.usf.edu libertia@mail.usf.edu
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Article Information

vol. 7 no. 1, bio029355

DOI 
https://doi.org/10.1242/bio.029355
PubMed 
29222175

Published By 
The Company of Biologists Ltd
Online ISSN 
2046-6390
History 
  • Received August 27, 2017
  • Accepted November 24, 2017
  • Published online January 17, 2018.
Posted online 
December 08, 2017
Copyright & Usage 
© 2018. Published by The Company of Biologists Ltd This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Article Versions

  • Previous version (December 8, 2017 - 06:43).
  • You are viewing the most recent version of this article.

Author Information

  1. Assunta Liberti1,2,*,‡,
  2. Ivana Zucchetti1,*,
  3. Daniela Melillo1,3,
  4. Diana Skapura4,
  5. Yoshimi Shibata5,
  6. Rosaria De Santis1,
  7. Maria Rosaria Pinto1,
  8. Gary W. Litman2 and
  9. Larry J. Dishaw2,‡
  1. 1Department of Animal Physiology and Evolution, Stazione Zoologica Anton Dohrn, Napoli 80121, Italy
  2. 2University of South Florida, Morsani College of Medicine, Department of Pediatrics, Tampa, FL 33606, USA
  3. 3Institute of Protein Biochemistry (IBP), National Research Council (CNR), Napoli 80131, Italy
  4. 4Molecular Genetics, Johns Hopkins All Children's Hospital, Saint Petersburg, FL 33701, USA
  5. 5Biomedical Science Department, Florida Atlantic University, Charles E. Schmidt College of Medicine, Boca Raton, FL 33431, USA
  1. ↵‡Authors for correspondence (ldishaw{at}health.usf.edu; libertia{at}mail.usf.edu)
    • ↵* These authors contributed equally to this work

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    Keywords

    • Inflammatory bowel disease
    • DSS-induced colitis
    • Ciona intestinalis
    • Chitin-rich mucus
    • VCBPs
    • Host-microbes interaction

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    Research Article
    Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis
    Assunta Liberti, Ivana Zucchetti, Daniela Melillo, Diana Skapura, Yoshimi Shibata, Rosaria De Santis, Maria Rosaria Pinto, Gary W. Litman, Larry J. Dishaw
    Biology Open 2018 7: bio029355 doi: 10.1242/bio.029355 Published 17 January 2018
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    Research Article
    Chitin protects the gut epithelial barrier in a protochordate model of DSS-induced colitis
    Assunta Liberti, Ivana Zucchetti, Daniela Melillo, Diana Skapura, Yoshimi Shibata, Rosaria De Santis, Maria Rosaria Pinto, Gary W. Litman, Larry J. Dishaw
    Biology Open 2018 7: bio029355 doi: 10.1242/bio.029355 Published 17 January 2018

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