REVIEW
- Symbiosis in the microbial world: from ecology to genome evolution
Summary: At a recent Company of Biologists workshop, evolutionary biologists discussed the major outstanding questions in symbiosis research.
RESEARCH ARTICLES
- Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice
Summary: S1P governs a fundamental aspect of skeletal development and homeostasis, mainly the maintenance and osteogenic differentiation of skeletogenic stem cells that are a source of osteoblast and chondrocyte lineages.
- Mechanical properties of silk of the Australian golden orb weavers Nephila pilipes and Nephila plumipes
Summary: Spider silk is a remarkably tough and extensible biomaterial. We identified macrostuctural and mechanical differences in outer web frame silk of two Australian orb-weaving spiders.
- Ecdysone signaling regulates specification of neurons with a male-specific neurite in Drosophila
Summary: The insect molting hormone ecdysone determines whether a single neuron develops a sex-specific structure, through crosstalk with signaling elements in a pathway dedicated to the sex-fate determination.
- Timing and context of dolphin clicks during and after mine simulator detection and marking in the open ocean
Summary: Dolphins wore cameras so we could hear them and watch them mark mine simulators. We observed rhythmic click trains, victory squeals, and click packets with their behavioral context.
- The histone deacetylase HDAC1 positively regulates Notch signaling during Drosophila wing development
Summary: The histone deacetylase HDAC1 acts as a positive regulator of Notch signaling during Drosophila wing development, and its depletion causes wing notches on the margin of adult wing.
- Spermine modulates fungal morphogenesis and activates plasma membrane H+-ATPase during yeast to hyphae transition
Summary: This study presents a new mechanistic model for the integrative role of the polyamine spermine and hormone auxin in the signaling of yeast-to-hypha transition, filling an important gap in fungal morphogenesis.
- Metabolism of the Pacific oyster, Crassostrea gigas, is influenced by salinity and modulates survival to the Ostreid herpesvirus OsHV-1
Summary: Environmental salinity influences energetic reserves, enzyme activity, membrane fatty acids of the Pacific oyster and modulates survival to viral infection.
- Sustained exercise-trained juvenile black carp (Mylopharyngodon piceus) at a moderate water velocity exhibit improved aerobic swimming performance and increased postprandial metabolic responses
Summary: Sustained exercise training at a moderate water velocity had positive effects on aerobic swimming performance and postprandial metabolic responses in juvenile black carp (Mylopharyngodon piceus).
- Human hepatocyte depletion in the presence of HIV-1 infection in dual reconstituted humanized mice
Summary: We describe a model that recapitulates multiple components of liver damage by HIV-1 infection as in humans, including reduced liver CD4+ cells, albumin levels, liver immune activation and human hepatocyte survival.
- How does the snakehead Channa argus survive in air? The combined roles of the suprabranchial chamber and physiological regulations during aerial respiration
Summary: The aerial survival of the northern snakehead could be involved with suprabranchial chamber respiration, and also with physiological regulations.
- Plastid translation is essential for lateral root stem cell patterning in Arabidopsis thaliana
Summary: Successful plastid gene expression is required for stem cell patterning in lateral root primordia as revealed by genetic and pharmacological impairment of plastid translation.
- A transgenic zebrafish model for the in vivo study of the blood and choroid plexus brain barriers using claudin 5
Summary: A novel transgenic zebrafish, using claudin 5a, represents an ideal model to study blood brain barrier and choroid plexus barrier development and function in vivo.
- Gemin4 is an essential gene in mice, and its overexpression in human cells causes relocalization of the SMN complex to the nucleoplasm
Summary: Gemin4 loss-of-function is recessive lethal in mice, whereas in cell culture its overexpression results in a dominant, gain-of-function relocalization of SMN and other Gemin proteins to the nucleus.
This issue
JUMP TO
Other journals from The Company of Biologists
First person interview – Mary Salcedo
Have you seen our interviews with early-career first authors of our papers? In the latest issue, first author Mary Salcedo discusses her latest Methods and Techniques paper in which a newly created method geometrically analyses 789 insect wings.
Find out how Pamela Imperadore’s Travelling Fellowship grant from The Company of Biologists took her to Germany, where she used new imaging techniques to investigate the cellular machinery underlying octopus arm regeneration. Don’t miss the next application deadline for 2020 travel, coming up on 29 November. Where will your research take you?
On the cover, David Coppola, Brent Craven and their colleagues refute a widely-debated theory of olfactory coding first suggested by the Nobel Laureate Lord Adrian over half a century ago.
Biology Open has strong credentials and publishing with us is easy and fast. BiO aims to provide rapid publication for scientifically sound observations and valid conclusions in developmental, cell, experimental and translational biology. Submit your paper here – you’ll be in good company!
Recent cell science highlights in BiO – Masamitsu Sato and colleagues show that the conserved microtubule-associated protein CLASP facilitates bundling of spindle microtubules in early mitosis.
Transfer to Biology Open
If your submission to one of our sister journals, Development, Journal of Cell Science, Journal of Experimental Biology or Disease Models & Mechanisms, is unsuccessful, you can transfer your paper and any reviews directly to Biology Open. The majority of papers transferred with reviews are accepted for publication - find out more.
BiO joins the Review Commons initiative
Biology Open is pleased to be a part of the new and exciting Review Commons initiative, launched by EMBO and ASAPbio. Streamlining the publishing process, Review Commons enables high-quality peer review to take place before journal submission. Papers submitted to Review Commons will be assessed independently of any journal, focusing solely on the paper’s scientific rigor and merit.
preLights - Mammalian Y RNAs are modified at discrete guanosine residues with N-glycans
Connor Rosen discusses his selected preprint by Carolyn Bertozzi, Ryan Flynn and their co-workers on the glycosylation of small non-coding RNAs in mammalian cells.