RESEARCH ARTICLES
- Viability of dietary substitution of live microalgae with dry Ulva rigida in broodstock conditioning of the Pacific oyster (Crassostrea gigas)
Summary: The use of an alternative diet with 25% microalgae replacement by dry macroalgae is beneficial during broodstock conditioning and allows the operation costs of bivalve hatcheries to be minimized.
- Short chain ceramides disrupt immunoreceptor signaling by inhibiting segregation of Lo from Ld Plasma membrane components
Summary: Our manuscript describes how perturbation of plasma membrane structure by short chain ceramides offers a general method for assessing functional roles for ordered lipid regions in membrane and cell biology.
- Prepulse inhibition in Drosophila melanogaster larvae
Summary: Prepulse inhibition (PPI) deficiency is observed in various psychiatric disorders. Here we demonstrate PPI in Drosophila and its association with psychiatric disease-related genes.
- Altered dynamics of scaRNA2 and scaRNA9 in response to stress correlates with disrupted nuclear organization
Summary: Stress conditions, including DNA damaging agents, and knockdown of nuclear proteins, including SMN and Drosha, alter the processing dynamics of scaRNA 2 and 9.
- Oxytocin receptor signaling contributes to olfactory avoidance behavior induced by an unpleasant odorant
Summary: Homozygous mice exhibited abnormal olfactory behaviors, namely failure in the acute avoidance of butyric acid and in habituation behavior, in the absence of a social context.
- Axial morphology and 3D neurocranial kinematics in suction-feeding fishes
Summary: Aspects of axial skeletal morphology and body shape correlate with 3D neurocranial motions in three species, generating hypotheses of how axial shape may impact cranial motions in fishes.
- CXCR4/SDF1 signalling promotes sensory neuron clustering in vitro
Summary: The signalling mechanisms directing sensory neuron gangliogenesis are not well understood. Here, we model this process through stem cell differentiation and show that CXCR4 signalling facilitates neural clustering.
- Physiological electric field works via the VEGF receptor to stimulate neovessel formation of vascular endothelial cells in a 3D environment
Summary: This study reports the effects of a direct current electrical field on endothelial neovessel formation in 3D culture. Endogenous EFs may promote angiogenesis of endothelial cells by activating the VEGF receptor signaling pathway.
- The soluble transhydrogenase UdhA affecting the glutamate-dependent acid resistance system of Escherichia coli under acetate stress
Summary: UdhA function stated in this study helps us to understand the physiological roles of UdhA affecting NADH production and Gad acid resistance system in E.coli in acetate environment.
- Drosophila mef2 is essential for normal mushroom body and wing development
Summary: Drosophila mef2 expression is restricted to subsets of mushroom body neurons, from the time of their differentiation to adulthood, and is essential for mushroom body formation.
- Characterization of diabetic neuropathy progression in a mouse model of type 2 diabetes mellitus
Summary: We characterized the main functional and structural diabetic neuropathy features during early-to-late phases of type 2 diabetes mellitus. This study aimed to identify a therapeutic window for new treatments.
- rebuff regulates apical luminal matrix to control tube size in Drosophila trachea
Summary: Novel function of Smad-like protein Rebuff in regulating tube size of Drosophila trachea through endocytosis of luminal matrix components.
- The small G protein Arl8 contributes to lysosomal function and long-range axonal transport in Drosophila
Summary: Drosophila Arl8 is essential for viability and is required for normal functioning of the late endocytic pathway and for long-range transport in axons.
- It works! Lumpfish can significantly lower sea lice infestation in large-scale salmon farming
Summary: Lumpfish are effective cleaner fish for biological delousing and can significantly lower average levels of pre-adult and female Lepeophtheirus salmonis and Caligus elongatus sea lice on Atlantic salmon.
- Metabolic rates, swimming capabilities, thermal niche and stress response of the lumpfish, Cyclopterus lumpus
Summary: Assessment of aerobic capacity and swimming behaviour of the lumpfish with swim tunnel respirometry at different acclimation temperatures and fish sizes, and measurements of haematological parameters in relation to exercise stress.
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Biology Open and COVID-19
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New funding scheme supports sustainable events
As part of our Sustainable Conferencing Initiative, we are pleased to announce funding for organisers that seek to reduce the environmental footprint of their event. The next deadline to apply for a Scientific Meeting grant is 26 March 2021.
Future Leader Review – early neurodegeneration of Alzheimer’s disease
A new Future Leader Review from Olayemi Olajide, Marcus Suvanto and Clifton Andrew Chapman evaluates the molecular mechanisms that may explain the vulnerability and susceptibility of the entorhinal cortex to early neurodegeneration during the pathogenesis of Alzheimer's disease.
Find out more about our Future Leader Reviews – they are an exclusive opportunity for early-career researchers who want to establish themselves in their field.
First author interviews
Catch up on our latest first author interviews to go behind the scenes of our latest research, find out more about the authors and hear from early-career researchers themselves how they’re finding life at the bench.
Retinal degeneration in Drosophila
Thank you to Elisabeth Knust and her team for their confocal image of a longitudinal section of an adult Drosophila retina, which brightens the cover of our latest issue. Read the research behind the cover.