This issue is currently being compiled. Articles in their final version of record are published here as soon as they are ready. The most recent articles appear at the top of the relevant section.
RESEARCH ARTICLES
- Ubiquitin-mediated proteasome degradation regulates optic fissure fusion
Summary: Optic fissure fusion, a key retinal morphogenic event highly sensitive to developmental signaling, is directly regulated by ubiquitin-mediated proteasomal degradation uncovering a novel regulatory pathway potentially correlated to incidence of coloboma.
- The Drosophila protein, Nausicaa, regulates lamellipodial actin dynamics in a Cortactin-dependent manner
Summary: The Drosophila Cortactin-binding protein Nausicaa regulates actin branching and lamellipodial dynamics through is anchoring of Cortactin in the lamellipodia.
- Spring-loaded inverted pendulum goes through two contraction-extension cycles during the single-support phase of walking
Summary: We quantitatively evaluate a simple model for human walking based on two-spring and find that this model describes many features of human walking.
- Intraspecific variation in metabolic rate and its correlation with local environment in the Chinese scorpion Mesobuthus martensii
Summary: Metabolic rate variation is observed between the two sexes and among populations in the Chinese scorpion, with the latter being correlated negatively with local mean temperature and positively with annual days of rainfall.
- Is blood cortisol or vateritic otolith composition associated with natal dispersal or reproductive performance on the spawning grounds of straying and homing hatchery-produced chum salmon (Oncorhynchus keta) in Southeast Alaska?
Summary: Straying mediates ecological interactions and gene flow between salmon populations. Understanding physiological controls and underlying causes of straying by hatchery-produced salmon may help managers minimize deleterious interactions.
- Effectors of the spindle assembly checkpoint are confined within the nucleus of Saccharomyces cerevisiae
Summary: The effectors of the spindle assembly checkpoint are confined with the nuclear compartment of budding yeast, and cannot exchange between nuclei in a binucleate zygote.
- Cell recovery by reversal of ferroptosis
Summary: Programmed cell death is generally assumed to be irreversible. Interestingly, we discovered reversible apoptosis. Here, we further demonstrate reversible ferroptosis, thereby adding a new example of reversible programmed cell death.
- Influence of arm swing on cost of transport during walking
Summary: Excessive arm swing reduces the vertical angular momentum and ground reaction moment, but not necessarily the energetic cost of transport.
- Eyes and negative phototaxis in juvenile crown-of-thorns starfish, Acanthaster species complex
Summary: The juvenile crown-of-thorns starfish has much smaller eyes than adults do, which results in worse spatial resolution. Still, they use the eyes for negative phototaxis seeking shelter.
- Evidence of dietary protein restriction regulating pupation height, development time and lifespan in Drosophila melanogaster
Summary: In studying protein-restricted diet-mediated interplay between major traits during pre-adult to adult stages in Drosophila melanogaster, we found various existing positive and negative correlations being challenged and supported upon differing diets.
- Zebra finch (Taeniopygia guttata) shift toward aerodynamically efficient flight kinematics in response to an artificial load
Summary: When equipped with an artificial load, zebra finch diverge from their typical flap-bounding pattern of flight, potentially reducing their muscular efficiency, and adopt more aerodynamically efficient kinematics.
- Suppressor of Fused regulates the proliferation of postnatal neural stem and precursor cells via a Gli3-dependent mechanism
Summary: Conditional deletion of Sufu causes dramatic expansion of neural stem/precursor cells in the neonatal ventricular-subventricular (SVZ) zone. This defect occurs through a Gli3-dependent mechanism resulting in the downregulation of Shh signaling.
- Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish
Summary: This study highlights Fgf3 in a novel context where it is part of a signalling pathway of critical importance for development of hypothalamic monoaminergic cells in zebrafish.
- An essential role of the mouse synapse-associated protein Syap1 in circuits for spontaneous motor activity and rotarod balance
Summary: Knockout of the Syap1 gene in mice causes a distinct motor behaviour phenotype characterised by reduced initial locomotor activity and impaired rotarod performance.
METHODS AND TECHNIQUES
- An instrumented centrifuge for studying mouse locomotion and behaviour under hypergravity
Summary: We present a system for exposing mice to hypergravity and measuring the effects on their locomotion and activity. We include details of the design and implementation, and example experimental data.
This issue
Other journals from The Company of Biologists
Cover article – Numb regulates cell tension required for mammary duct elongation
Image credit: Sudipa J. Chatterjee
Luke McCaffrey and colleagues show that Numb regulates cortical cell tension, which is necessary to maintain proper cell shape and packing density during mammary duct elongation.
The combination of light sheet fluorescent microscopy and flow cytometry allows assessment of proliferation and tumor growth of human GBM inside zebrafish, find Veronica Akle and team, making it a useful model to identify effective anti-proliferative agents in a preclinical setting.
Have you seen our interviews with the early-career first authors of our papers? Recently, we caught up with first authors Gigi Lau, Nick Barts and Xiao-Zhi Cheng.
Biology Open has strong credentials and publishing with us is easy and fast. BiO aims to provide rapid publication for scientifically sound observations and valid conclusions in developmental, cell, experimental and translational biology. Submit your paper here; you’ll be in good company.
Recent experimental biology highlights in BiO – Jia-Jia Xu, Shi-Jian Fu and Cheng Fu show that predator-naive carp show a typical stress response when exposed to predators and can instinctually discriminate between natural predators and non-predators.
Transfer to Biology Open
If your submission to one of our other journals, Development, Journal of Cell Science, Journal of Experimental Biology or Disease Models & Mechanisms, is unsuccessful, did you know you can transfer your paper and any reviews directly to Biology Open? The majority of papers transferred with reviews are accepted for publication. Find out how here.
preLights - Co-reviewing and ghostwriting by early career researchers in the peer review of manuscripts
Gautam Dey and Tessa Sinnige highlight a preprint from Gary McDowell et al. which discusses the widespread uncredited participation by early career researchers in peer review.