Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Interviews
    • Sign up for alerts
  • About us
    • About BiO
    • Editors and Board
    • Editor biographies
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact BiO
    • Advertising
    • Feedback
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

User menu

  • Log in

Search

  • Advanced search
Biology Open
  • COB
    • About The Company of Biologists
    • Development
    • Journal of Cell Science
    • Journal of Experimental Biology
    • Disease Models & Mechanisms
    • Biology Open

supporting biologistsinspiring biology

Biology Open

Advanced search

RSS   Twitter   Facebook   YouTube

  • Home
  • Articles
    • Accepted manuscripts
    • Issue in progress
    • Latest complete issue
    • Issue archive
    • Archive by article type
    • Interviews
    • Sign up for alerts
  • About us
    • About BiO
    • Editors and Board
    • Editor biographies
    • Grants and funding
    • Journal Meetings
    • Workshops
    • The Company of Biologists
    • Journal news
  • For authors
    • Submit a manuscript
    • Aims and scope
    • Presubmission enquiries
    • Article types
    • Manuscript preparation
    • Cover suggestions
    • Editorial process
    • Promoting your paper
    • Open Access
  • Journal info
    • Journal policies
    • Rights and permissions
    • Media policies
    • Reviewer guide
    • Sign up for alerts
  • Contact
    • Contact BiO
    • Advertising
    • Feedback

 

  You have access

  Open access

June, 2019; 8 (6)

RESEARCH ARTICLES

  • Open Access
    Krüppel-like factor 6 mediates pulmonary angiogenesis in rat experimental hepatopulmonary syndrome and is aggravated by bone morphogenetic protein 9
    Yihui Yang, Hongfu Yu, Congwen Yang, Yunfei Zhang, Xiangfa Ai, Xiaobo Wang, Kaizhi Lu, Bin Yi
    Biology Open 2019 8: bio040121 doi: 10.1242/bio.040121 Published 26 June 2019

    Summary: Krüppel-like factor 6, which is triggered by pulmonary injury and promoted by bone morphogenetic protein 9, mediates pulmonary angiogenesis in rat experimental hepatopulmonary syndrome and then aggravates lung dysfunction.

  • Open Access
    Overexpression of long noncoding RNA GAS5 suppresses tumorigenesis and development of gastric cancer by sponging miR-106a-5p through the Akt/mTOR pathway
    Shuaijun Dong, Xiefu Zhang, Dechun Liu
    Biology Open 2019 8: bio041343 doi: 10.1242/bio.041343 Published 26 June 2019

    Summary: GAS5, a tumor suppressor, was confirmed to suppress tumorigenesis and development of gastric cancer by sponging miR-106a-5p through the Akt/mTOR pathway, which provides a novel regulatory axis of GC progression.

  • Open Access
    Ambient temperature effects on stress-induced hyperthermia in Svalbard ptarmigan
    Andreas Nord, Lars P. Folkow
    Biology Open 2019 8: bio043497 doi: 10.1242/bio.043497 Published 20 June 2019

    Summary: Handling in severe cold causes hyperthermia in well-insulated Svalbard ptarmigan. Hence, pronounced cooling in cold-handled poorly insulated birds likely reflects high heat-loss rate rather than a different physiological response.

  • Open Access
    Ubiquitin-mediated proteasome degradation regulates optic fissure fusion
    Warlen Pereira Piedade, Sydney Veith, Jakub Konrad Famulski
    Biology Open 2019 8: bio044974 doi: 10.1242/bio.044974 Published 17 June 2019

    Summary: Optic fissure fusion, a key retinal morphogenic event highly sensitive to developmental signaling, is directly regulated by ubiquitin-mediated proteasomal degradation uncovering a novel regulatory pathway potentially correlated to incidence of coloboma.

  • Open Access
    The Drosophila protein, Nausicaa, regulates lamellipodial actin dynamics in a Cortactin-dependent manner
    Meghan E. O'Connell, Divya Sridharan, Tristan Driscoll, Ipsita Krishnamurthy, Wick G. Perry, Derek A. Applewhite
    Biology Open 2019 8: bio038232 doi: 10.1242/bio.038232 Published 17 June 2019

    Summary: The Drosophila Cortactin-binding protein Nausicaa regulates actin branching and lamellipodial dynamics through its anchoring of Cortactin in the lamellipodia.

  • Open Access
    Spring-loaded inverted pendulum goes through two contraction-extension cycles during the single-support phase of walking
    Gabriel Antoniak, Tirthabir Biswas, Nelson Cortes, Siddhartha Sikdar, Chanwoo Chun, Vikas Bhandawat
    Biology Open 2019 8: bio043695 doi: 10.1242/bio.043695 Published 14 June 2019

    Summary: We quantitatively evaluate a simple model for human walking based on two-spring and find that this model describes many features of human walking.

  • Open Access
    Intraspecific variation in metabolic rate and its correlation with local environment in the Chinese scorpion Mesobuthus martensii
    Wei Wang, Gao-Ming Liu, De-Xing Zhang
    Biology Open 2019 8: bio041533 doi: 10.1242/bio.041533 Published 14 June 2019

    Summary: Metabolic rate variation is observed between the two sexes and among populations in the Chinese scorpion, with the latter being correlated negatively with local mean temperature and positively with annual days of rainfall.

  • Open Access
    Is blood cortisol or vateritic otolith composition associated with natal dispersal or reproductive performance on the spawning grounds of straying and homing hatchery-produced chum salmon (Oncorhynchus keta) in Southeast Alaska?
    Casey J. McConnell, Shannon Atkinson, Dion Oxman, Peter A. H. Westley
    Biology Open 2019 8: bio042853 doi: 10.1242/bio.042853 Published 12 June 2019

    Summary: Straying mediates ecological interactions and gene flow between salmon populations. Understanding physiological controls and underlying causes of straying by hatchery-produced salmon may help managers minimize deleterious interactions.

  • Open Access
    Effectors of the spindle assembly checkpoint are confined within the nucleus of Saccharomyces cerevisiae
    Lydia R. Heasley, Jennifer G. DeLuca, Steven M. Markus
    Biology Open 2019 8: bio037424 doi: 10.1242/bio.037424 Published 12 June 2019

    Summary: The effectors of the spindle assembly checkpoint are confined with the nuclear compartment of budding yeast, and cannot exchange between nuclei in a binucleate zygote.

  • Open Access
    Cell recovery by reversal of ferroptosis
    Ho Man Tang, Ho Lam Tang
    Biology Open 2019 8: bio043182 doi: 10.1242/bio.043182 Published 11 June 2019

    Summary: Programmed cell death is generally assumed to be irreversible. Interestingly, we discovered reversible apoptosis. Here, we further demonstrate reversible ferroptosis, thereby adding a new example of reversible programmed cell death.

  • Open Access
    Influence of arm swing on cost of transport during walking
    Myriam L. de Graaf, Juul Hubert, Han Houdijk, Sjoerd M. Bruijn
    Biology Open 2019 8: bio039263 doi: 10.1242/bio.039263 Published 10 June 2019

    Summary: Excessive arm swing reduces the vertical angular momentum and ground reaction moment, but not necessarily the energetic cost of transport.

  • Open Access
    Eyes and negative phototaxis in juvenile crown-of-thorns starfish, Acanthaster species complex
    Camilla Korsvig-Nielsen, Mike Hall, Cherie Motti, Anders Garm
    Biology Open 2019 8: bio041814 doi: 10.1242/bio.041814 Published 10 June 2019

    Summary: The juvenile crown-of-thorns starfish has much smaller eyes than adults do, which results in worse spatial resolution. Still, they use the eyes for negative phototaxis seeking shelter.

  • Open Access
    Evidence of dietary protein restriction regulating pupation height, development time and lifespan in Drosophila melanogaster
    Sudhakar Krittika, Alisha Lenka, Pankaj Yadav
    Biology Open 2019 8: bio042952 doi: 10.1242/bio.042952 Published 6 June 2019

    Summary: In studying protein-restricted diet-mediated interplay between major traits during pre-adult to adult stages in Drosophila melanogaster, we found various existing positive and negative correlations being challenged and supported upon differing diets.

  • Open Access
    Zebra finch (Taeniopygia guttata) shift toward aerodynamically efficient flight kinematics in response to an artificial load
    Anthony B. Lapsansky, Jennifer A. Igoe, Bret W. Tobalske
    Biology Open 2019 8: bio042572 doi: 10.1242/bio.042572 Published 6 June 2019

    Summary: When equipped with an artificial load, zebra finch diverge from their typical flap-bounding pattern of flight, potentially reducing their muscular efficiency, and adopt more aerodynamically efficient kinematics.

  • Open Access
    Suppressor of Fused regulates the proliferation of postnatal neural stem and precursor cells via a Gli3-dependent mechanism
    Hector G. Gomez, Hirofumi Noguchi, Jesse Garcia Castillo, David Aguilar, Samuel J. Pleasure, Odessa R. Yabut
    Biology Open 2019 8: bio039248 doi: 10.1242/bio.039248 Published 6 June 2019

    Summary: Conditional deletion of Sufu causes dramatic expansion of neural stem/precursor cells in the neonatal ventricular-subventricular (SVZ) zone. This defect occurs through a Gli3-dependent mechanism resulting in the downregulation of Shh signaling.

  • Open Access
    Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish
    Isabel Reuter, Jana Jäckels, Susanne Kneitz, Jochen Kuper, Klaus-Peter Lesch, Christina Lillesaar
    Biology Open 2019 8: bio040683 doi: 10.1242/bio.040683 Published 5 June 2019

    Summary: This study highlights Fgf3 in a novel context where it is part of a signalling pathway of critical importance for development of hypothalamic monoaminergic cells in zebrafish.

  • Open Access
    An essential role of the mouse synapse-associated protein Syap1 in circuits for spontaneous motor activity and rotarod balance
    Cora R. von Collenberg, Dominique Schmitt, Thomas Rülicke, Michael Sendtner, Robert Blum, Erich Buchner
    Biology Open 2019 8: bio042366 doi: 10.1242/bio.042366 Published 5 June 2019

    Summary: Knockout of the Syap1 gene in mice causes a distinct motor behaviour phenotype characterised by reduced initial locomotor activity and impaired rotarod performance.

METHODS & TECHNIQUES

  • Open Access
    Establishing simple image-based methods and a cost-effective instrument for toxicity assessment on circadian rhythm dysregulation in fish
    Gilbert Audira, Bonifasius Putera Sampurna, Stevhen Juniardi, Sung-Tzu Liang, Yu-Heng Lai, Liwen Han, Chung-Der Hsiao
    Biology Open 2019 8: bio041871 doi: 10.1242/bio.041871 Published 26 June 2019

    Summary: A cost-effective device and two methods to measure the circadian rhythm in diurnal and nocturnal fish, providing a reliable entry point for toxicity assessment on circadian rhythm dysregulation in fish.

  • Open Access
    An instrumented centrifuge for studying mouse locomotion and behaviour under hypergravity
    Benjamin J. H. Smith, James R. Usherwood
    Biology Open 2019 8: bio043018 doi: 10.1242/bio.043018 Published 14 June 2019

    Summary: We present a system for exposing mice to hypergravity and measuring the effects on their locomotion and activity. We include details of the design and implementation, and example experimental data.

FIRST PERSON

  • Open Access
    First person – Camilla Elinor Korsvig-Nielsen
    Biology Open 2019 8: bio045120 doi: 10.1242/bio.045120 Published 10 June 2019
  • Open Access
    First person – Myriam de Graaf and Juul Hubert
    Biology Open 2019 8: bio045138 doi: 10.1242/bio.045138 Published 10 June 2019
  • Open Access
    First person – Sudhakar Krittika
    Biology Open 2019 8: bio044966 doi: 10.1242/bio.044966 Published 6 June 2019
Back to top
PreviousNext
Previous IssueNext Issue

This issue

Biology Open: 8 (6)
  • Table of Contents (PDF)
  • About the Cover
  • Table of Contents
  • Index by author
  • Issue info (PDF)

RSSRSS Icon

JUMP TO

  • RESEARCH ARTICLES
  • METHODS & TECHNIQUES
  • FIRST PERSON

  Alert me to new issues of Biology Open

  • Accepted manuscripts
  • Most-read
Loading
  • Open Access

    Integrated Analysis of Cell Shape and Movement in Moving Frame

    Yusri Dwi Heryanto, Chin-Yi Cheng, Yutaka Uchida, Kazushi Mimura, Masaru Ishii, Ryo Yamada
    PDF
  • Open Access

    Avoiding being stung or bitten – prey capture behaviors of the ant-eating Texas horned lizard (Phrynosoma cornutum)

    Ismene Fertschai, Wade C. Sherbrooke, Matthias Ott, Boris P. Chagnaud
    PDF
  • Open Access

    A Zebrafish Forward Genetic Screen Identifies an Indispensible Threonine Residue in the Kinase Domain of PRKD2

    Panagiota Giardoglou, Despina Bournele, Misun Park, Stavroula Kanoni, George V. Dedoussis, Susan F. Steinberg, Panos Deloukas, Dimitris Beis
    PDF
  • Open Access

    Interdomain interactions regulate the localization of a lipid transfer protein at ER-PM contact sites

    Bishal Basak, Harini Krishnan, Raghu Padinjat
    PDF
  • Open Access

    The thermal dependence and molecular basis of physiological color change in Takydromus septentrionalis (Lacertidae)

    Kun Guo, Jun Zhong, Lin Zhu, Fan Xie, Yu Du, Xiang Ji
    PDF
See more accepted manuscripts...

Other journals from The Company of Biologists

Development

Journal of Cell Science

Journal of Experimental Biology

Disease Models & Mechanisms

Advertisement

Biology Open and COVID-19

We are aware that the COVID-19 pandemic is having an unprecedented impact on researchers worldwide. The Editors of all The Company of Biologists’ journals have been considering ways in which we can alleviate concerns that members of our community may have around publishing activities during this time. Read about the actions we are taking at this time.

Please don’t hesitate to contact the Editorial Office if you have any questions or concerns.


Future Leader Review - Cardiac myosin super relaxation

A new Future Leader Review by Manuel Schmid and Christopher Toepfer discusses the rapidly-expanding field of myosin super relaxation in the context of cardiovascular disease. Read the full Review and their accompanying interview.

Find out more about our Future Leader Reviews – they are an exclusive opportunity for early-career researchers who want to establish themselves in their field.


An interview with Roberta Azzarelli

In an interview, first author Roberta Azzarelli discusses her 3D model of glioblastoma and shares her thoughts on how to improve the professional lives of early-career researchers: formal mentorship programmes, a clearly structured career path and taking part in initiatives such as the Node Network.


News from our sister journals

Development continues to run a successful new webinar series, Development presents…, while Journal of Cell Science has recently welcomed Esperanza Agullo-Pascual as FocalPlane’s new Community Manager. Journal of Experimental Biology’s new special issue highlights the role of comparative biology in tackling climate change and Liz Patton, the new Editor-in-Chief of Disease Models & Mechanisms, sets out her visions and priorities.

Articles

  • Accepted manuscripts
  • Issue in progress
  • Latest complete issue
  • Issue archive
  • Archive by article type
  • Interviews
  • Sign up for alerts

About us

  • About BiO
  • Editors and Board
  • Editor biographies
  • Grants and funding
  • Journal Meetings
  • Workshops
  • The Company of Biologists

For Authors

  • Submit a manuscript
  • Aims and scope
  • Presubmission enquiries
  • Article types
  • Manuscript preparation
  • Cover suggestions
  • Editorial process
  • Promoting your paper
  • Open Access

Journal Info

  • Journal policies
  • Rights and permissions
  • Media policies
  • Reviewer guide
  • Sign up for alerts

Contact

  • Contact BiO
  • Advertising
  • Feedback

Twitter   YouTube   LinkedIn

© 2021   The Company of Biologists Ltd   Registered Charity 277992