This issue is currently being compiled. Articles in their final version of record are published here as soon as they are ready. The most recent articles appear at the top of the relevant section.
REVIEW
- Uncharted routes: exploring the relevance of auxin movement via plasmodesmata
Summary: The review discusses the occurrence and biological relevance of auxin transport via plasmodesmata in plants. Physical modes of transport of this hormone, feedbacks on its movement and evolutionary aspects are included.
RESEARCH ARTICLES
- RhoGAP RGA-8 supports morphogenesis in C. elegans by polarizing epithelia
Summary: RGA-8, a protein with membrane binding and actin regulatory motifs, promotes embryonic morphogenesis by localizing active CDC-42 in developing epithelia, and controlling actin and actin motors during cell movements.
- Antibiotics in hives and their effects on honey bee physiology and behavioral development
Summary: Antibiotic treatments in bee colonies cause an increase or decrease in rate of behavioral development and lipid stores of workers, affecting fat body–interaction, likely through effects on microbiota.
- The role of macrophage migration inhibitory factor in promoting benign prostatic hyperplasia epithelial cell growth by modulating COX-2 and P53 signaling
Summary: This study found high levels of MIF expression in BPH epithelium. MIF promoted BPH epithelial cell growth and participated in the progression of BPH by regulating COX-2 and P53 signaling
- Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy
Summary: GRP78 is highly expressed in the lung cancer tissue, and targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by endoplasmic reticulum stress and autophagy.
- Influence of maternal diet on offspring survivorship, growth, and reproduction in a sheetweb spider
Summary: A single meal immediately before oviposition is sufficient to influence offspring survival, growth, and daughters' reproduction in the sheetweb spider Hylyphantes graminicola.
- Royal jelly attenuates metabolic defects in a Drosophila mutant with elevated TORC1 activity
Summary: Royal jelly (RJ) modulates the reactive oxygen species (ROS) levels and some metabolic defects that associated with hyper TORC1 activity in a Drosophila model.
- Squids use multiple escape jet patterns throughout ontogeny
Summary: In this study, we examine the hydrodynamics and kinematics of escape jets in squids throughout ontogeny using 2D/3D velocimetry and high-speed videography.
- Amyloid-beta peptide and phosphorylated tau in the frontopolar cerebral cortex and in the cerebellum of toothed whales: aging versus hypoxia
Summary: Immunohistochemical analysis showed positive immunolabeling for amyloid-beta peptide and phosphorylated tau in the cerebral and cerebellar cortex of toothed whales. These findings could be linked to hypoxic phenomena.
METHODS & TECHNIQUES
- Assessing methods to quantitatively validate TGFβ-dependent autophagy
Summary: Using various tools including western blotting and immunofluorescence microscopy, it was observed that autophagic flux probes are the most robust tools to quantitatively assess cellular autophagy.
- Efficient and crucial quality control of HAP1 cell ploidy status
Summary: Sharing an effective procedure to quality control the near-haploid HAP1 cells for standardized comparison to CRISPR/Cas9 modified versions and demonstrating the need for controlling the spontaneous diploidization of HAP1 cultures.
- Progressive tracking: a novel procedure to facilitate manual digitization of videos
Summary: Progressive tracking is a novel procedure for manual point digitization in markerless videos. It allows for tracking points efficiently without the need to click all individual frames.
- Inducible modulation of miR-204 levels in a zebrafish melanoma model
Summary: Sarti et al. describe miniCoopR-I inducible vectors, a refined tool to study the impact exerted by pigmentation on melanogenesis (during embryonic development) versus melanomagenesis (in adult zebrafish).
- An improved whole life cycle culture protocol for the hydrozoan genetic model Clytia hemisphaerica
Summary: We developed a reliable whole life cycle culture method for the hydrozoan jellyfish Clytia hemisphaerica, a model animal for genetics and developmental biology.
This issue
Other journals from The Company of Biologists
Biology Open and COVID-19
We are aware that the COVID-19 pandemic is having an unprecedented impact on researchers worldwide. The Editors of all The Company of Biologists’ journals have been considering ways in which we can alleviate concerns that members of our community may have around publishing activities during this time. Read about the actions we are taking at this time.
Please don’t hesitate to contact the Editorial Office if you have any questions or concerns.
Sustainable Conferencing with The Company of Biologists
A new initiative spearheaded by Directors Sally Lowell, Kate Storey, Alastair Downey and Holly Shiels will provide information, technology and grants to help the community run conferences in a more sustainable way.
Publishing ethics in the era of paper mills
In a new Editorial, Managing Editor Rachel Hackett and Editor-in-Chief Steven Kelly write about misconduct in publishing scientific research and highlight BiO’s practices to ensure that the profits from the hard work of scientists continues to inspire the next generation of researchers.
Shifting away from the business-as-usual approach to research conferences
Chelsie Counsell, Franziska Elmer and Judith Lang discuss their experience of organising a global, virtual coral reef conference, including the key steps, with a timeline, required to organise it.
Interview – Evgeniya Karpova and Evgenii Komyshev
In an interview, co-first authors Evgeniya Karpova and Evgenii Komyshev discuss the implications of their new method of counting Drosophila offspring using the SeedCounter mobile app.
Open science saves lives: lessons from the COVID-19 pandemic
Over on preLights, Jonny Coates and Gautam Dey discuss a preprint by Besançon et al., which identifies some of the challenges with how the COVID-19 literature has been created and shared.