Table 1. Cell-mediated contraction of floating and attached collagen gels.

Cells were incubated in collagen solutions (106 cells per ml of collagen) and the collagen was allowed to polymerize. For floating gels, the collagen gels were floated on cell culture medium. For the attached gels, collagen was allowed to adhere to plastic dishes; cells then developed tension in the gels prior to their release from the underlying dishes. The reduction of collagen gel diameter over time (fitted by linear regression) was used as a measure of cell-mediated contraction. Data are mean┬▒standard error of the mean slope of the reduction of gel diameters over time (┬Ám/hr). Significant differences between indicated groups and controls are marked by ** for P<0.01 and * for P<0.05.

Table 1.