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Actin cytoskeleton

  • RESEARCH ARTICLE
    Actin cytoskeleton remodeling defines a distinct cellular function for adhesion G protein-coupled receptors ADGRL/latrophilins 1, 2 and 3
    Judith S. Cruz-Ortega, Antony A. Boucard
    Biology Open 2019 8: bio039826 doi: 10.1242/bio.039826 Published 23 April 2019

    Summary: Synapses involve the adhesion function of latrophilins within existing neuronal extensions. We show that latrophilins engage the actin cytoskeleton, both constitutively and upon ligand stimulation, to dictate cell extension patterns.

  • METHODS & TECHNIQUES
    PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins
    Daniela Leyton-Puig, Katarzyna M. Kedziora, Tadamoto Isogai, Bram van den Broek, Kees Jalink, Metello Innocenti
    Biology Open 2016 5: 1001-1009; doi: 10.1242/bio.019570

    Summary: We show that proper PFA fixation allows high-quality super-resolution imaging of the actin cytoskeleton and can outperform gold-standard glutaraldehyde fixation for imaging of actin-binding proteins.

  • RESEARCH ARTICLE
    Association between tensin 1 and p130Cas at focal adhesions links actin inward flux to cell migration
    Zhihai Zhao, Song Hui Tan, Hiroaki Machiyama, Keiko Kawauchi, Keigo Araki, Hiroaki Hirata, Yasuhiro Sawada
    Biology Open 2016 5: 499-506; doi: 10.1242/bio.016428

    Summary: Tensin 1 links phosphorylated Cas to actin inward flux, facilitating the force transmission from the motile system (i.e. actomyosin contraction) to the stationary parts (i.e. adhesion complexes) in migrating cells.

  • RESEARCH ARTICLE
    Evolutionarily conserved sites in yeast tropomyosin function in cell polarity, transport and contractile ring formation
    Susanne Cranz-Mileva, Brittany MacTaggart, Jacquelyn Russell, Sarah E. Hitchcock-DeGregori
    Biology Open 2015 4: 1040-1051; doi: 10.1242/bio.012609
  • RESEARCH ARTICLE
    Insights into the osteoblast precursor differentiation towards mature osteoblasts induced by continuous BMP-2 signaling
    Omar F. Zouani, Lila Rami, Yifeng Lei, Marie-Christine Durrieu
    Biology Open 2013 2: 872-881; doi: 10.1242/bio.20134986
  • RESEARCH ARTICLE
    Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry
    Irina V. Gorudko, Alexey V. Sokolov, Ekaterina V. Shamova, Natalia A. Grudinina, Elizaveta S. Drozd, Ludmila M. Shishlo, Daria V. Grigorieva, Sergey B. Bushuk, Boris A. Bushuk, Sergey A. Chizhik, Sergey N. Cherenkevich, Vadim B. Vasilyev, Oleg M. Panasenko
    Biology Open 2013 2: 916-923; doi: 10.1242/bio.20135314

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