Alternative splicing
- Whole-transcriptome splicing profiling of E7.5 mouse primary germ layers reveals frequent alternative promoter usage during mouse early embryogenesis
Summary: This study seeks to capture the alternative splicing landscape during mouse gastrulation, underlining the potential importance of alternative promoter usage in mammalian early embryogenesis.
- The Crumbs_C isoform of Drosophila shows tissue- and stage-specific expression and prevents light-dependent retinal degeneration
Summary: Loss of Crb_C, one protein isoform encoded by Drosophila crumbs, results in light-dependent retinal degeneration, but does not affect any of the other crumbs-specific functions.
- Novel myristoylation of the sperm-specific hexokinase 1 isoform regulates its atypical localization
Summary: Dual acylation (i.e. myristoylation and palmitoylation) regulates the atypical localization of sperm-specific hexokinase 1 isoform and thus is essential for ‘rewiring’ of glycolytic network.