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Bioelectricity

  • METHODS & TECHNIQUES
    Defined extracellular ionic solutions to study and manipulate the cellular resting membrane potential
    Mattia Bonzanni, Samantha L. Payne, Miryam Adelfio, David L. Kaplan, Michael Levin, Madeleine J. Oudin
    Biology Open 2020 9: bio048553 doi: 10.1242/bio.048553 Published 14 January 2020

    Summary: We describe a simplified roadmap to study the role of bioelectricity, in particular individual ions, in cell biological processes.

  • RESEARCH ARTICLE
    HCN4 ion channel function is required for early events that regulate anatomical left-right patterning in a nodal and lefty asymmetric gene expression-independent manner
    Vaibhav P. Pai, Valerie Willocq, Emily J. Pitcairn, Joan M. Lemire, Jean-François Paré, Nian-Qing Shi, Kelly A. McLaughlin, Michael Levin
    Biology Open 2017 6: 1445-1457; doi: 10.1242/bio.025957

    Summary: We identify a novel, developmental role for HCN4 channels and reveal a new Nodal-Lefty-Pitx2-independent, non-canonical mechanism upstream of organ positioning during embryonic left-right patterning. This article has an associated First Person interview with the first author of the paper as part of the supplementary information.

  • RESEARCH ARTICLE
    Light-activation of the Archaerhodopsin H+-pump reverses age-dependent loss of vertebrate regeneration: sparking system-level controls in vivo
    Dany Spencer Adams, Ai-Sun Tseng, Michael Levin
    Biology Open 2013 2: 306-313; doi: 10.1242/bio.20133665

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