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calpain

  • RESEARCH ARTICLE
    Developing fluorescence sensor probe to capture activated muscle-specific calpain-3 (CAPN3) in living muscle cells
    Koichi Ojima, Shoji Hata, Fumiko Shinkai-Ouchi, Mika Oe, Susumu Muroya, Hiroyuki Sorimachi, Yasuko Ono
    Biology Open 2020 9: bio048975 doi: 10.1242/bio.048975 Published 4 September 2020

    Summary: Our research is the first report of developing sensor probes to detect activated-CAPN3 in cultured skeletal muscle cells.

  • RESEARCH ARTICLE
    Epstein-Barr virus-encoded LMP2A stimulates migration of nasopharyngeal carcinoma cells via the EGFR/Ca2+/calpain/ITGβ4 axis
    Jiezhen Liang, Shixing Zheng, Xue Xiao, Jiazhang Wei, Zhe Zhang, Ingemar Ernberg, Liudmila Matskova, Guangwu Huang, Xiaoying Zhou
    Biology Open 2017 6: 914-922; doi: 10.1242/bio.024646

    Summary: LMP2A expression in nasopharyngeal carcinoma cells increases EGFR activation and cytosolic Ca2+, subsequently stimulates calpain-dependent cleavage of ITGβ4 and enhances cell motility.

  • RESEARCH ARTICLE
    Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin
    Elena Marcassa, Marzia Raimondi, Tahira Anwar, Eeva-Liisa Eskelinen, Michael P. Myers, Gianluca Triolo, Claudio Schneider, Francesca Demarchi
    Biology Open 2017 6: 551-562; doi: 10.1242/bio.022806

    Summary: ER stress triggers calpain-dependent Bif-1 activation and induction of autophagosome maturation by promoting ATG9/Bif-1 vesicle trafficking and fusion with LC3 bodies.

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