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cell invasion

  • RESEARCH ARTICLE
    The transcription factor Spalt and human homologue SALL4 induce cell invasion via the dMyc-JNK pathway in Drosophila
    Jie Sun, Junzheng Zhang, Dan Wang, Jie Shen
    Biology Open 2020 9: bio048850 doi: 10.1242/bio.048850 Published 24 March 2020

    Summary: We investigated the molecular mechanism of how sal/SALL4 regulates cell invasion and found that this process depends on the dMyc-JNK pathway.

  • RESEARCH ARTICLE
    Role of ALDH1A1 and HTRA2 expression in CCL2/CCR2-mediated breast cancer cell growth and invasion
    Qingting Hu, Megan Myers, Wei Fang, Min Yao, Gage Brummer, Justin Hawj, Curtis Smart, Cory Berkland, Nikki Cheng
    Biology Open 2019 8: bio040873 doi: 10.1242/bio.040873 Published 28 June 2019

    Summary: Chemokines are known to regulate immune cell recruitment during inflammation. This report characterizes novel molecular mechanisms through which CCL2/CCR2 chemokine signaling in breast cancer cells regulates growth and invasion.

  • RESEARCH ARTICLE
    MiR-142 modulates human pancreatic cancer proliferation and invasion by targeting hypoxia-inducible factor 1 (HIF-1α) in the tumor microenvironments
    Yebin Lu, Niandong Ji, Wei Wei, Weijia Sun, Xuejun Gong, Xitao Wang
    Biology Open 2017 6: 252-259; doi: 10.1242/bio.021774

    Summary: Our findings provide insights to the functional mechanism of miR-142, suggesting that the miR-142/HIF-1α axis may interfere with the proliferative and invasive property of pancreatic cancer cells.

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