CFTR
- Vardenafil increases intracellular accumulation of the most prevalent mutant cystic fibrosis transmembrane conductance regulator (CTFR) in human bronchial epithelial cells
Summary: Our findings support the view that vardenafil, a phosphodiesterase type 5 inhibitor, partially rescues F508del protein through cGMP/PKG-independent mechanisms in cystic fibrosis cell line.
- WNK1 and p38-MAPK distribution in ionocytes and accessory cells of euryhaline teleost fish implies ionoregulatory function
Summary: Fish opercular epithelium ionocytes and accessory cells have WNK family kinases that may regulate paracellular and transcellular ion transport.