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Chick embryo

  • RESEARCH ARTICLE
    Niclosamide rescues microcephaly in a humanized in vivo model of Zika infection using human induced neural stem cells
    Dana M. Cairns, Devi Sai Sri Kavya Boorgu, Michael Levin, David L. Kaplan
    Biology Open 2018 7: bio031807 doi: 10.1242/bio.031807 Published 29 January 2018

    Summary: Injecting hiNSCs into developing chick brains and systemically infecting with ZIKV produces embryos with severe microcephaly. Using this humanized model we show that niclosamide rescues ZIKV-induced microcephaly and decreases infection of hiNSCs in vivo.

  • RESEARCH ARTICLE
    Constitutively active Notch1 converts cranial neural crest-derived frontonasal mesenchyme to perivascular cells in vivo
    Sophie R. Miller, Surangi N. Perera, Clare V. H. Baker
    Biology Open 2017 6: 317-325; doi: 10.1242/bio.023887

    Summary: Sustained Notch1 activation is sufficient to drive cranial neural crest-derived frontonasal mesenchyme to adopt a perivascular (mural) cell fate in developing chick embryos.

  • RESEARCH ARTICLE
    Chick embryo xenograft model reveals a novel perineural niche for human adipose-derived stromal cells
    Ingrid R. Cordeiro, Daiana V. Lopes, José G. Abreu, Katia Carneiro, Maria I. D. Rossi, José M. Brito
    Biology Open 2015 4: 1180-1193; doi: 10.1242/bio.010256
  • RESEARCH ARTICLE
    A chicken model of pharmacologically-induced Hirschsprung disease reveals an unexpected role of glucocorticoids in enteric aganglionosis
    Jean-Marie Gasc, Maud Clemessy, Pierre Corvol, Hervé Kempf
    Biology Open 2015 4: 666-671; doi: 10.1242/bio.201410454
  • RESEARCH ARTICLE
    PTEN is involved in modulation of vasculogenesis in early chick embryos
    Yan Li, Xiao-yu Wang, Ting Wu, Manli Chuai, Kenneth Ka Ho Lee, Li-jing Wang, Xuesong Yang
    Biology Open 2013 2: 587-595; doi: 10.1242/bio.20133988

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