Drosophila
- Prickle isoforms control the direction of tissue polarity by microtubule independent and dependent mechanisms
Summary: Learning how Pk and Sple differentially interpret directional cues allows a broader understanding of the varied signals and mechanisms linking the core module to tissue axes in planar cell polarity.
- Glucose modulates Drosophila longevity and immunity independent of the microbiota
Summary: Dietary glucose improves both longevity and immunity in adult Drosophila through a mechanism independent of the intestinal microbiota.
- Clueless is a conserved ribonucleoprotein that binds the ribosome at the mitochondrial outer membrane
Summary: Clueless is a ribonucleoprotein that is crucial for mitochondrial function. Here we show Clueless can bind the ribosome at the mitochondrial outer membrane, suggesting it may play a role in mitochondrial co-translational import.
- Tissue-specific tagging of endogenous loci in Drosophila melanogaster
Summary: Here we describe an easily applicable method that allows C-terminal protein tagging at endogenous loci in a tissue- or cell type-specific manner in Drosophila melanogaster.
- Dynamic microtubule organization and mitochondrial transport are regulated by distinct Kinesin-1 pathways
Summary: Highly polarized Drosophila bristle cells reveal that dynamic microtubule organization and mitochondrial transport are regulated by distinct Kinesin-1 pathways, and a novel mode of coordination between Khc and Dhc in mitochondrial transport.
- Differentiated muscles are mandatory for gas-filling of the Drosophila airway system
Summary: During embryogenesis in Drosophila melanogaster, without involving the nervous system, somatic muscles control terminal differentiation of the airway system by stimulating gas-filling before hatching.
- Context-specific comparison of sleep acquisition systems in Drosophila
Summary: Multiple sleep acquisition systems provide efficient and accurate methods for measuring sleep duration in Drosophila, while video tracking and multibeam analysis allow for increased flexibility of behavioral paradigms and greater resolution of sleep architecture.
- Epigenetic regulator Lid maintains germline stem cells through regulating JAK-STAT signaling pathway activity
Summary: This study provides new insights into the biological functions of a histone demethylase and sheds light on the interaction between epigenetic mechanisms and signaling pathways in regulating stem cell activities.