Embryogenesis
- Specificity, redundancy and dosage thresholds among gata4/5/6 genes during zebrafish cardiogenesis
Summary: Targeted mutations were generated for each of the three gata4/5/6 genes in zebrafish to define functions for individual or combinations of these related transcription factors during cardiogenesis.
- High-throughput live-imaging of embryos in microwell arrays using a modular specimen mounting system
Summary: This Methods & Techniques article describes a customizable device for mounting and live-imaging a wide range of tissues and species; complete design files and instructions for assembly are included.
- The hidden function of egg white antimicrobials: egg weight-dependent effects of avidin on avian embryo survival and hatchling phenotype
Summary: This is the first experimental study to evaluate the effects of increased concentration of egg white antimicrobial protein avidin on embryo viability, hatchling morphology and immune phenotype in birds.
- αE-catenin-dependent mechanotransduction is essential for proper convergent extension in zebrafish
Summary: Cadherin adhesions transduce tension across the junction-actomyosin axis into proportional biochemical responses via α-catenin. Here we show for the first time how this function of the cadherin complex is important during zebrafish morphogenesis.