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Excitotoxicity

  • RESEARCH ARTICLE
    Hypoxia-ischemia alters distribution of lysosomal proteins in rat cortex and hippocampus
    M. Troncoso, N. Bannoud, L. Carvelli, J. Asensio, A. Seltzer, M. A. Sosa
    Biology Open 2018 7: bio036723 doi: 10.1242/bio.036723 Published 25 October 2018

    Summary: Hypoxia ischemia (HI) induces an increase of gliosis and redistribution of prosaposin and cathepsin D into the cytosol of rat hippocampus. This could be triggered by LAMP-1 cleavage in HI.

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