Focal Adhesion Kinase
- Wound-induced polyploidization is dependent on Integrin-Yki signaling
Summary: Conserved focal adhesion genes, mys and Fak, enable efficient wound repair by inducing polyploid cell growth via cell fusion and Yki-dependent endoreplication.
- Basal constriction during midbrain–hindbrain boundary morphogenesis is mediated by Wnt5b and focal adhesion kinase
Summary: Focal adhesion kinase acts downstream of Wnt5b to mediate basal constriction of neuroepithelial cells during the formation of the midbrain–hindbrain boundary.