Golgi
- Acid sphingomyelinase regulates the localization and trafficking of palmitoylated proteins
Summary: Acid sphingomyelinase (ASM) regulates palmitoylated protein trafficking and localization.
- The Golgi matrix protein giantin is required for normal cilia function in zebrafish
Summary: Morpholino knockdown of Golgb1/giantin leads to a severe cilopathy phenotype twinned with longer, misshapen cilia. Stable mutants have a very mild phenotype, indicative of compensation, but still have longer cilia.
- The roles of Syx5 in Golgi morphology and Rhodopsin transport in Drosophila photoreceptors
Summary: Unlike Rab6-deficiency which affects only apical transport pathways, Syx5-deficiency inhibits all of polarized transport pathways, implying that these two genes are working in distinct stages of intra-Golgi transport.
- The role of acroblast formation during Drosophila spermatogenesis
Summary: This study demonstrates that retrograde tethering complexes are necessary to form a functional acroblast, which is essential for normal nuclear elongation and acrosome formation during Drosophila spermatogenesis.
- An antibody toolkit for the study of membrane traffic in Drosophila melanogaster
Summary: We report the generation and characterization of set of monoclonal and polyclonal antibodies for labeling the major compartments of the secretory and endocytic pathways in Drosophila melanogaster.