Induced pluripotent stem cells
- Collagen vitrigel promotes hepatocytic differentiation of induced pluripotent stem cells into functional hepatocyte-like cells
Summary: We found that collagen vitrigel membrane used as scaffold potentiates differentiation of human induced pluripotent stem cells to differentiate into mature hepatocyte-like cells that exhibit mature functions of the hepatocytes.
- Osteoblast differentiation of equine induced pluripotent stem cells
Summary: Horse iPSCs can be turned directly into bone forming cells but the efficiency is affected by the donor horse. Less variability is observed using different iPSC lines derived from the same horse.
- Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells
Summary: This study demonstrates differentiation of adult dermal fibroblast-derived iPSCs into neural crest and corneal endothelial-like cells, which could be a valuable tool for investigating the mechanisms of cornea endothelial disease.
- Low extracellular potassium prolongs repolarization and evokes early afterdepolarization in human induced pluripotent stem cell-derived cardiomyocytes
Summary: This is the first study showing the effects of low extracellular potassium on the electrophysiological properties of human induced pluripotent stem cell-derived long QT cardiomyocytes at single and multicellular level.