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Low-density lipoprotein receptor (LDLR)

  • RESEARCH ARTICLE
    A lipidomics study reveals hepatic lipid signatures associating with deficiency of the LDL receptor in a rat model
    Hong Yu Wang, Chao Quan, Chunxiu Hu, Bingxian Xie, Yinan Du, Liang Chen, Wei Yang, Liu Yang, Qiaoli Chen, Bin Shen, Bian Hu, Zhihong Zheng, Haibo Zhu, Xingxu Huang, Guowang Xu, Shuai Chen
    Biology Open 2016 5: 979-986; doi: 10.1242/bio.019802

    Summary: An LDL receptor knockout rat model was generated which offers a new hypercholesterolemia model. A lipidomics analysis reveals hepatic lipid signatures associating with LDLR deficiency in rats.

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