LPS
- Neuronal changes and cognitive deficits in a multi-hit rat model following cumulative impact of early life stressors
Summary: This study is the first of its kind that practically investigated the combined exposure of major early life stressors like protein malnourishment and viral and bacterial infections on the nervous system.
- Pioglitazone abolishes cognition impairments as well as BDNF and neurotensin disturbances in a rat model of autism
Summary: Exposure of rats to lipopolysaccharide during gestation induced autistic-like behaviors in the juvenile offspring. Daily postnatal pioglitazone treatment abolished cognition impairments as well as brain-derived neurotrophic factor and neurotensin disturbances.