Microtubules
- Tau interferes with axonal neurite stabilization and cytoskeletal composition independently of its ability to associate with microtubules
Summary: Tau inhibits axonal transport by blocking kinesin translocation or as kinesin cargo. Tau capable and incapable of microtubule binding inhibited transport equally, indicating inhibition of axonal transport as kinesin cargo.
- Microtubule assembly and pole coalescence: early steps in Caenorhabditis elegans oocyte meiosis I spindle assembly
Summary: This paper documents requirements for several regulators of microtubule assembly and stability during the early steps of acentrosomal meiotic spindle assembly in Caenorhabditis elegans oocytes.
- GFP-Forked, a genetic reporter for studying Drosophila oocyte polarity
Summary: The novel asymmetric Forked network could be used as a genetic reporter for visualizing and studying oocyte polarity.
- Centrioles without microtubules: a new morphological type of centriole
Summary: Centrioles without microtubules in larvae cells of parasitoid wasps duplicate and form primary cilia without microtubules, in nymph and imago cells centrioles acquire a ‘normal’ structure with nine microtubules triplets.
- Phosphatase-regulated recruitment of the spindle- and kinetochore-associated (Ska) complex to kinetochores
Summary: Feedback between protein phosphatases and the spindle- and kinetochore-associated (Ska) complex regulates chromosome movement and the metaphase-to-anaphase cell cycle transition. This article has an associated First Person interview with the first author of the paper as part of the supplementary information.
- Endogenous AJAP1 associates with the cytoskeleton and attenuates angiogenesis in endothelial cells
Summary: Depletion of AJAP1 in endothelial cells can increase angiogenic-like sprouting and cell migration. In addition, AJAP1 associates with microtubules in these cells.