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mTOR

  • RESEARCH ARTICLE
    The effects of AICAR and rapamycin on mitochondrial function in immortalized mitochondrial DNA mutator murine embryonic fibroblasts
    Vedad Delic, Kenyaria Noble, Sandra Zivkovic, Tam-Anh Phan, Christian Reynes, Yumeng Zhang, Oluwakemi Phillips, Charles Claybaker, Yen Ta, Vinh B. Dinh, Josean Cruz, Tomas A. Prolla, Patrick C. Bradshaw
    Biology Open 2018 7: bio033852 doi: 10.1242/bio.033852 Published 16 November 2018

    Summary: A novel mitochondrial DNA mutator murine embryonic fibroblast cell line was created and the effects of the anti-aging compounds rapamycin and AICAR on energy metabolism in these cells was determined.

  • RESEARCH ARTICLE
    Using genetic buffering relationships identified in fission yeast to reveal susceptibilities in cells lacking hamartin or tuberin function
    Ashyad Rayhan, Adam Faller, Ryan Chevalier, Alannah Mattice, Jim Karagiannis
    Biology Open 2018 7: bio031302 doi: 10.1242/bio.031302 Published 17 January 2018

    Summary: We exploit the BioGRID gene interaction database to identify and characterize susceptibilities in fission yeast cells lacking tsc1 or tsc2, orthologs of the human TSC1 and TSC2 tumor suppressor genes.

  • RESEARCH ARTICLE
    The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole
    Ivan Tattoli, Dana J. Philpott, Stephen E. Girardin
    Biology Open 2012 1: 1215-1225; doi: 10.1242/bio.20122840

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