Neural development
- Dynamic neurotransmitter specific transcription factor expression profiles during Drosophila development
Summary: Transcriptome profiling of cholinergic, GABAergic and glutamatergic neurons in Drosophila identified multiple transcription factors as potential regulators of neurotransmitter fate.
- FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain
Summary: Regulating the fine structure of cell surface carbohydrates provides a mechanism for fine tuning the formation of morphogen gradients in the embryonic mouse fore-brain.
- Cross-species functional analyses reveal shared and separate roles for Sox11 in frog primary neurogenesis and mouse cortical neuronal differentiation
Summary: Sox11 acts to designate neurons in both mouse and frog brains, but orthologs are not functionally redundant. These data show evolutionary conservation of Sox11 function with molecular divergence.