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Neural development

  • RESEARCH ARTICLE
    Dynamic neurotransmitter specific transcription factor expression profiles during Drosophila development
    Alicia Estacio-Gómez, Amira Hassan, Emma Walmsley, Lily Wong Le, Tony D. Southall
    Biology Open 2020 9: bio052928 doi: 10.1242/bio.052928 Published 3 June 2020

    Summary: Transcriptome profiling of cholinergic, GABAergic and glutamatergic neurons in Drosophila identified multiple transcription factors as potential regulators of neurotransmitter fate.

  • RESEARCH ARTICLE
    FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain
    Wai-Kit Chan, David J. Price, Thomas Pratt
    Biology Open 2017 6: 1933-1942; doi: 10.1242/bio.028605

    Summary: Regulating the fine structure of cell surface carbohydrates provides a mechanism for fine tuning the formation of morphogen gradients in the embryonic mouse fore-brain.

  • RESEARCH ARTICLE
    Cross-species functional analyses reveal shared and separate roles for Sox11 in frog primary neurogenesis and mouse cortical neuronal differentiation
    Chao Chen, Jing Jin, Garrett A. Lee, Elena Silva, Maria Donoghue
    Biology Open 2016 5: 409-417; doi: 10.1242/bio.015404

    Summary: Sox11 acts to designate neurons in both mouse and frog brains, but orthologs are not functionally redundant. These data show evolutionary conservation of Sox11 function with molecular divergence.

  • RESEARCH ARTICLE
    VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1
    Chun-Lei Wang, Fu-Lei Tang, Yun Peng, Cheng-Yong Shen, Lin Mei, Wen-Cheng Xiong
    Biology Open 2012 1: 1248-1257; doi: 10.1242/bio.20122451

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