Notch signaling
- Jagged1 protein processing in the developing mammalian lens
Summary: The Notch pathway ligand protein Jagged1 undergoes multiple catalytic cleavages, regulated by Adam proteases and the gamma-secretase complex, during mammalian lens development, similar to Notch receptor proteins.
- The protein phosphatase 4 complex promotes the Notch pathway and wingless transcription
Summary: The protein phosphatase 4 complex promotes Notch signaling and target gene expression during Drosophila wing development.