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Notch signaling

  • RESEARCH ARTICLE
    Notch signaling governs the expression of glypican Dally to define the stem cell niche
    Songhua Zhao, Chan Wu, Zhiyang Gao, Xin Li, Zheng Guo, Zhaohui Wang
    Biology Open 2020 9: bio047696 doi: 10.1242/bio.047696 Published 10 January 2020

    Summary: Spatial regulation of a cell surface glycoprotein defines the territory of germline stem cells.

  • RESEARCH ARTICLE
    Jagged1 protein processing in the developing mammalian lens
    Mina Azimi, Nadean L. Brown
    Biology Open 2019 8: bio041095 doi: 10.1242/bio.041095 Published 26 March 2019

    Summary: The Notch pathway ligand protein Jagged1 undergoes multiple catalytic cleavages, regulated by Adam proteases and the gamma-secretase complex, during mammalian lens development, similar to Notch receptor proteins.

  • RESEARCH ARTICLE
    The protein phosphatase 4 complex promotes the Notch pathway and wingless transcription
    Eric T. Hall, Tirthadipa Pradhan-Sundd, Faaria Samnani, Esther M. Verheyen
    Biology Open 2017 6: 1165-1173; doi: 10.1242/bio.025221

    Summary: The protein phosphatase 4 complex promotes Notch signaling and target gene expression during Drosophila wing development.

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