Xenopus
- De novo transcription of multiple Hox cluster genes takes place simultaneously in early Xenopus tropicalis embryos
Summary: qPCR analysis for de novo transcription of hox genes suggest that temporal collinearity is not held for all hox genes during early development of Xenopus tropicalis.
- HCN4 ion channel function is required for early events that regulate anatomical left-right patterning in a nodal and lefty asymmetric gene expression-independent manner
Summary: We identify a novel, developmental role for HCN4 channels and reveal a new Nodal-Lefty-Pitx2-independent, non-canonical mechanism upstream of organ positioning during embryonic left-right patterning. This article has an associated First Person interview with the first author of the paper as part of the supplementary information.
- Vestigial-like 3 is a novel Ets1 interacting partner and regulates trigeminal nerve formation and cranial neural crest migration
Summary: Here, we provide the first description of Vgll3 function during vertebrate development. Vgll3 is a new partner of Ets1 and regulates trigeminal nerve formation and cranial neural crest cell migration.
- Amyloids assemble as part of recognizable structures during oogenesis in Xenopus
Summary: Non-membrane-bound nuclear particles in Xenopus oocytes responsible for RNA transcription, modification and processing contain proteins assembled into amyloids as part of normal development.